Protein Alignment Hsp70Bc and hsp-4

DIOPT Version :9

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 627
• Identity: 360/627 - (57%)
• Similarity: 475/627 - (75%)
• Gaps: 15/627 - (2%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT--DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||||||||:::|:|||||||||||.|||||||:  ..||||||.||||:.:||.||:||
 Worm    33 IGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINPENTIFD 97

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||.|::..:.:|:||||||:|....||.:.|:...|:|:|.|||:|:|||||||:.||:|
 Worm    98 AKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGSETKQFTPEEVSAMVLTKMKQIAESY 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||..:.:||:||||||||:|:|||||||.||||||:||||||||||:||||||. .||||:|:||
 Worm   163 LGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 226

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||:||||.| :|||.:|.|||||||||||.|::.:..:.:|:|..||||.:.||:::|
 Worm   227 LGGGTFDVSLLTIDSG-VFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDNRAVQKL 290

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |...|:|||.||:..:..|||::||:|:||...::||:||||..||||.||:||:|.|.||.|.|
 Worm   291 RREVEKAKRALSTQHQTKIEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDADMKK 355

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVL 390
            ..:|:||||||||||||||.|::::|:||..:..|||||||||||||||.::.| :.:|   ||:
 Worm   356 TDVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGGVENTG---DVV 417

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALG 455
            |:||.||:|||||.||||||||.||..||.|:::.|||.:|:|..|||.:|||||.|..||:.||
 Worm   418 LLDVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVMDNHKLG 482

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            .||::||||||||||||||||::|.||||:|||::..||....:||.||..|||..:|:||:|:|
 Worm   483 NFDVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIERMINDA 547

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQSV--EQAPAGKLDEADKNSVLDKCNETIRWLDSNTT 583
            :|:|.:|:..::::.|||.||:|.:.:|..:  ::...|||.:.||.|:.......|.||.||..
 Worm   548 DKFAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEWLGSNQD 612

  Fly   584 AEKEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQ 625
            |..||...:.:||.....||::|::     :|||.|....::
 Worm   613 ASTEENKEQKKELESVVQPIVSKLY-----SAGGQGEQASEE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	360/627 (57%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	242/376 (64%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	359/619 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720