Protein Alignment Hsp70Bc and Hspa13

DIOPT Version :10

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_084477.1
• Gene: Hspa13 / 110920
• MGIID: 1309463
• Length: 471
• Species: Mus musculus
• Alignment Length: 422
• Identity: 166/422 - (39%)
• Similarity: 241/422 - (57%)
• Gaps: 51/422 - (12%)

  Fly     4 IGIDLGTTYSCVGVY--QHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            |||||||||..|||:  ..|||::|.::.|:.:.||.|:|||.:..:|..:......||:||::|
Mouse    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDGDVYVGYESLELADSNPQNTIYD 98

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||.||:.:...::..::..:||||:...|..:..|. ..|:...:||.:.|.:|.|:||.||.|
Mouse    99 AKRFIGKIFTPEELEAEVGRYPFKVLHRNGMAEFSVT-SNETIIVSPEFVGSRLLLKLKEMAEEY 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||..:.:|||:|||.|:..||.:|..|.::|||.:||:||||||||:||||.|  .....||:.|
Mouse   163 LGMPVANAVISVPAEFDLQQRNSTIQAANLAGLKILRVINEPTAAAMAYGLHK--VDVFYVLVID 225

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||.|||:|. .:|.:|..|:.:|:..|||:||:.||:.||.:|..:.| ..|.|....:.||
Mouse   226 LGGGTLDVSLLN-KQGGMFLTRAMSGNNKLGGQDFNQRLLQHLYKEIYQTY-GFLPSRKEEIHRL 288

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQD------------------------------------ 290
            |.|.|..|..|:....|.:.:....||:|
Mouse   289 RQAVEMVKLNLTIHQSAQVSVLLTVEGKDSKEPQNGDSELPKDQLTPGDGHHVNRVFRPGLSESK 353

  Fly   291 -------FYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLL 348
                   |.|:|||..|:.|..|||:..|.|:::.|.:..:||.:|.::||||||||||:::.::
Mouse   354 SGKSQVLFETEVSRKLFDALNEDLFQKILVPIQQVLKEGLLDKTEIDEVVLVGGSTRIPRIRQVI 418

  Fly   349 QEFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            |||| ||:.|.|::||.||..|.|:||.|..|
Mouse   419 QEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	166/422 (39%)
Hspa13	NP_084477.1	ASKHA_NBD_HSP70_HSPA13	10..452	CDD:466835	166/422 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	317..350		1/32 (3%)