Protein Alignment Hsp70Bb and SSA4

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_011029.3
• Gene: SSA4 / 856840
• SGDID: S000000905
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 644
• Identity: 452/644 - (70%)
• Similarity: 524/644 - (81%)
• Gaps: 10/644 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |:|||||||||||..:.:.:|||||||||||||||||||||:||||||.||||.||||.||||||
Yeast     4 AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDA 68

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            |||||||:|||::..|.||:||||:..||||.:.||||||:|.|.|||||||:|||||||||.:|
Yeast    69 KRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFL 133

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..:.|||:||||||||||||||||||.|||||||||||||||||:||||||..:.|.|||||||
Yeast   134 GTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDL 198

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:|:|||| :|||::|||||||||||||:|||..||||||||.||||.:|.|:|||||
Yeast   199 GGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLR 262

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            |||||||||||||.:.:||||:||||.||||.::|||||||||||||:||:||||.|.|:|:||.
Yeast   263 TAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKS 327

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||.:||||||||||||||.|:.:||:||..|.|||||||||||||||||||:||||...||:||:
Yeast   328 QIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLL 392

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||||||||||||||:|||||.||..||.|:::.||||:||||||.|||:||||..|||||.||.|
Yeast   393 DVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKF 457

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|||||||||||||||||||:||||||||||.|..|||:..|||.|||||||:.:||:||.||||
Yeast   458 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEK 522

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586
            :..|||:..||:.::|.||||.|.:|.|| |.....|:.|.|...:.....:.|.|||::..|..
Yeast   523 FKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAAST 587

  Fly   587 EEFDHKMEELTRHCSPIMTKMHQQGAGAAGG-PGAN--CGQQAGGFGG-YSGPTVEEVD 641
            ||:..:.:||....:|||:|.:    ||||| |||.  .|..||..|. .:||||||||
Yeast   588 EEYKERQKELEGVANPIMSKFY----GAAGGAPGAGPVPGAGAGPTGAPDNGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	450/642 (70%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	450/642 (70%)