Protein Alignment Hsp70Bb and ECM10

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 619
• Identity: 306/619 - (49%)
• Similarity: 420/619 - (67%)
• Gaps: 31/619 - (5%)

  Fly     4 IGIDLGTTYSCVGVYQHGKV-EIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||.|.|.:.: ||| .||.|.:|:|||||.|||| |.|||:|:|||.|..:|..||:|.
Yeast    30 IGIDLGTTNSAVAIME-GKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINSENTLFA 93

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .||||||:::|.::..|:...|||:|  |:|     ....:..::.::|.:|...:|.|||||||
Yeast    94 TKRLIGRRFEDAEVQRDINQVPFKIVKHSNG-----DAWVEARNRTYSPAQIGGFILNKMKETAE 153

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVL- 193
            |||.:|:.:||:||||||||:|||||||||.|.||||||::||||||||||||||:   |..|:
Yeast   154 AYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKS---EPKVIA 215

  Fly   194 IFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRAL 258
            :|||||||||:|||.||.| :|||:||.|||||||||||..|:..:...||::...||.::..|:
Yeast   216 VFDLGGGTFDISILDIDNG-IFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSNDRMAV 279

  Fly   259 RRLRTAAERAKRTLSS--STEATIE-IDALFEG-QDFYTKVSRARFEELCADLFRNTLQPVEKAL 319
            :|:|.|||:||..|||  |||..:. |.|...| :......||.:.|.:.|.|...|:.||:|||
Yeast   280 QRIREAAEKAKIELSSTLSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVDPVKKAL 344

  Fly   320 NDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSG 384
            .||::....|.|::||||.:|:|||...:::.| ||:.:.::|||||||.|||:|||:|||:
Yeast   345 KDARITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVLSGE--- 405

  Fly   385 KIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTK 449
             :.||||:||.||||||||.|||.||||.||..||.|:::.|||.:..|..|.::|::|||.:.|
Yeast   406 -VTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQGERELVK 469

  Fly   450 DNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEID 514
            ||..:|.|.|:||||||:|.||||||||:|||||:|||||::::.|..:||:....| ||..|||
Yeast   470 DNKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASG-LSDTEID 533

  Fly   515 RMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLD 579
            |||||||:|.::|...|..|.:.|..:....:.:.|:::. .||||:.|...:.|:.: ::|.|.
Yeast   534 RMVNEAERYKNQDRARRNAIETANKADQLANDTENSIKEF-EGKLDKTDSQRLKDQIS-SLRELV 596

  Fly   580 SNTTAEKEEFDH----KMEELTRHCSPIMTKMHQ 609
            |.:.|..|..|.    |::.|......:..::::
Yeast   597 SRSQAGDEVNDDDVGTKIDNLRTSSMKLFEQLYK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	306/619 (49%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	201/383 (52%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	306/619 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810