Protein Alignment Hsp70Bb and SSZ1

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_011931.2
• Gene: SSZ1 / 856461
• SGDID: S000001106
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 543
• Identity: 164/543 - (30%)
• Similarity: 277/543 - (51%)
• Gaps: 61/543 - (11%)

  Fly     2 PAIGIDLGTTYSCVG-VYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |.|||..|.|.|.:. :.....|::|||..|.|..||.:::...:...|..|..|:..||:||:.
Yeast     4 PVIGITFGNTSSSIAYINPKNDVDVIANPDGERAIPSALSYVGEDEYHGGQALQQLIRNPKNTII 68

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIG-VEYKGESK--RFAPEEISSMVLTKMKET 127
            :.:..||..:|...:::.....| .|..||   |:| |..:||.|  :...:|:.|..|.::|..
Yeast    69 NFRDFIGLPFDKCDVSKCANGAP-AVEVDG---KVGFVISRGEGKEEKLTVDEVVSRHLNRLKLA 129

  Fly   128 AEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 192
            ||.|:|.::.:||:|||..|::.|:.|.|.:....||.:::.||||:||.||:......:.:.||
Yeast   130 AEDYIGSAVKEAVLTVPTNFSEEQKTALKASAAKIGLQIVQFINEPSAALLAHAEQFPFEKDVNV 194

  Fly   193 LIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRA 257
            ::.|.||...|.:::.:..| :|.:.:||.|..|||::.|..||.:.|.||::||:.:.|.|.|:
Yeast   195 VVADFGGIRSDAAVIAVRNG-IFTILATAHDLSLGGDNLDTELVEYFASEFQKKYQANPRKNARS 258

  Fly   258 LRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDA 322
            |.:|:..:...|:|||::|.|||.||:|.:|.|::..::|.|:|.:...:|......|:..:..|
Yeast   259 LAKLKANSSITKKTLSNATSATISIDSLADGFDYHASINRMRYELVANKVFAQFSSFVDSVIAKA 323

  Fly   323 KMDKGQIHDIVLVGGSTRIPKVQSLLQ-------EFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            ::|...|..::|.||.:..||:.:.|:       |....:|.|.|.||:|..|.|||:||.::|.
Yeast   324 ELDPLDIDAVLLTGGVSFTPKLTTNLEYTLPESVEILGPQNKNASNNPNELAASGAALQARLISD 388

  Fly   381 DQSGKIQDVL---LVDVAPLS--LGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQV 440
            ..:.::.:.|   :|:...|.  :|:..|.|....::......|.::..|......:   ..|.|
Yeast   389 YDADELAEALQPVIVNTPHLKKPIGLIGAKGEFHPVLLAETSFPVQKKLTLKQAKGD---FLIGV 450

  Fly   441 YEGE--------RAMTKDNNA----------------------LGT--FDLSGIPPAPRGVPQIE 473
            |||:        ..:.|:.||                      |||  .:| ||..| .||   |
Yeast   451 YEGDHHIEEKTLEPIPKEENAEEDDESEWSDDEPEVVREKLYTLGTKLMEL-GIKNA-NGV---E 510

  Fly   474 VTFDLDANGILNVSAKEMSTGKA 496
            :.|:::.:|.|.|:|:::.||.|
Yeast   511 IIFNINKDGALRVTARDLKTGNA 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	164/543 (30%)
SSZ1	NP_011931.2	ASKHA_NBD_HSP70_ScSsz1p-like	4..386	CDD:466830	129/386 (33%)