Protein Alignment Hsp70Bb and KAR2

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_012500.3
• Gene: KAR2 / 853418
• SGDID: S000003571
• Length: 682
• Species: Saccharomyces cerevisiae
• Alignment Length: 618
• Identity: 376/618 - (60%)
• Similarity: 471/618 - (76%)
• Gaps: 9/618 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDAK 68
            ||||||||||||.|.::||.||:||:||||.|||||||||.||||||.||||||.||:||:||.|
Yeast    53 IGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIK 117

  Fly    69 RLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYLG 133
            ||||.||:|..:.:|:||.||.||:..|||.:.|..|||.|.|.|||||.|:|.|||:.||.|||
Yeast   118 RLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDYLG 182

  Fly   134 ESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDLG 198
            ..:|.||:||||||||:|||||||||.|||||||||:|||||||:||||||:.| |..::::|||
Yeast   183 TKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDK-EHQIIVYDLG 246

  Fly   199 GGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLRT 263
            |||||||:|:|:.| :|||::|:|||||||||||.::|..|.:.||:|:..|:..|.:||.:|:.
Yeast   247 GGTFDVSLLSIENG-VFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKR 310

  Fly   264 AAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQ 328
            .||:|||.|||.....||||:..:|.|....::||:||||..|||:.||:||||.|.|:.::|..
Yeast   311 EAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKD 375

  Fly   329 IHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVD 393
            :.|||||||||||||||.||:.:|.||..:..|||||||||||||||.:|||::.  ::|::|:|
Yeast   376 VDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEG--VEDIVLLD 438

  Fly   394 VAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTFD 458
            |..|:|||||.|||||.||:||..||.|:::.|||..||||.|.|:||||||||:||||.||.|:
Yeast   439 VNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFE 503

  Fly   459 LSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEKY 523
            |:||||||||||||||||.|||||||.|||.:..|||:::|||.||||||:|.||||||.||||:
Yeast   504 LTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKF 568

  Fly   524 ADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSN-TTAEKE 587
            |.||...:.::.|||.||:|..::|..|......||:|.||.::||..|:.:.|||.| .||..|
Yeast   569 ASEDASIKAKVESRNKLENYAHSLKNQVNGDLGEKLEEEDKETLLDAANDVLEWLDDNFETAIAE 633

  Fly   588 EFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGA 620
            :||.|.|.|::...||.:|::    |.|.|.||
Yeast   634 DFDEKFESLSKVAYPITSKLY----GGADGSGA 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	376/618 (61%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	238/374 (64%)
KAR2	NP_012500.3	HSP70	52..654	CDD:394970	371/604 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720