Protein Alignment Hsp70Bb and SSA2

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_013076.1
• Gene: SSA2 / 850636
• SGDID: S000003947
• Length: 639
• Species: Saccharomyces cerevisiae
• Alignment Length: 646
• Identity: 450/646 - (69%)
• Similarity: 533/646 - (82%)
• Gaps: 17/646 - (2%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |:|||||||||||..:.:.:|:|||||||||||||:|.|||:||||||.||||.||||.||||||
Yeast     4 AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDA 68

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||.::||::..||||:|||::...|||:|.||:|||:|.|.||:||||||.|||||||:||
Yeast    69 KRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYL 133

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..:.|||:||||||||||||||||||.|||||||||||||||||:||||||..| |.:||||||
Yeast   134 GAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGK-EEHVLIFDL 197

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:|:|::| :|||::|||||||||||||||||.|..:|||||.||||.:|.|||||||
Yeast   198 GGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLR 261

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||.:.::|||:||||.||||.::|||||||||||||:||.||||.|.|||:||.
Yeast   262 TACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKS 326

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            |:.:||||||||||||||.|:.::|:||..|.|||||||||||||||||||:||:|.|.||:||:
Yeast   327 QVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLL 391

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||||||||||||||||||||.||..||.|:::.||||:||||||.|||:|||||.|||||.||.|
Yeast   392 DVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKF 456

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|||||||||||||||||||:|:||||||||.|..|||:..|||.|||||||:.:|::||.||||
Yeast   457 ELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEK 521

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKE 587
            :.:||||..|||.|:|.|||..:::|.::.:| ..||::|||::|..|..|||.||||||||.||
Yeast   522 FKEEDEKESQRIASKNQLESIAYSLKNTISEA-GDKLEQADKDAVTKKAEETIAWLDSNTTATKE 585

  Fly   588 EFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGG-------YSGPTVEEVD 641
            |||.:::||....:|||:|::|.|       ||..|...|||.|       ..||||||||
Yeast   586 EFDDQLKELQEVANPIMSKLYQAG-------GAPEGAAPGGFPGGAPPAPEAEGPTVEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	448/644 (70%)
SSA2	NP_013076.1	PTZ00009	4..639	CDD:240227	448/644 (70%)