Protein Alignment Hsp70Bb and hspa12a

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001417784.2
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 670
• Species: Danio rerio
• Alignment Length: 670
• Identity: 136/670 - (20%)
• Similarity: 228/670 - (34%)
• Gaps: 226/670 - (33%)

  Fly    19 QHGKVEIIANDQGNRTTPSYVAFTDSERLI--------GDP-AKNQ-----VAMNPRNTVFDAKR 69
            :|..|.::|.|.|..::....|||.....|        ||| ..||     :.:.| :..|.:..
Zfish    49 RHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTP-DKKFHSFG 112

  Fly    70 LIGRKYDDPKIAEDMKHW----PFKV---------------VSDGGKPKIGVEYKGESKRFAPEE 115
            ...|.:.......:.|.|    .||:               .::|.|.| .::....:..|..|:
Zfish   113 YAARDFYHDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK-ALDIFAYALAFFKEQ 176

  Fly   116 ISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPT 174
                .|.::.:.|.|....:....||||||.:....:|..::|.:.|.|      :.|.|..||.
Zfish   177 ----ALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIALEPE 237

  Fly   175 AAAL--------------------AYGLDKN---------------------------------- 185
            ||::                    .|....|
Zfish   238 AASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELWSEL 302

  Fly   186 LKGERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDNRLVTHLAEEFKR 245
            .:|:|.|:: |.||||.|:::  :.:.||.|.|:...:|..:  :|.: :|:..|.....::|..
Zfish   303 AEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKLLCKIFGQDFID 366

  Fly   246 KYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV-----------SRAR 299
            ::|   ...|.|...|..|.|..||..:......:.|:..|...|:|.|.           |...
Zfish   367 QFK---IKRPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGHSVEHALRKSNVD 428

  Fly   300 FEELCAD------------LFRNTLQPVEKALNDAKMDKGQIHDI---VLVGGSTRIPKVQSLLQ 349
            |.:..:.            ||:.|:..:.:.|.:. .|:.::.||   .||||....|.:|..:|
Zfish   429 FVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGGFAESPLLQQAVQ 492

  Fly   350 EFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIE 413
            ....|:: .:.|..|..:   ..::.|:|.| |.|     ::.|..:||:.|:    ||:.:.:|
Zfish   493 NMLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS-----IIKVRRSPLTYGV----GVLNRFVE 544

  Fly   414 --------------RNCRIPCKQTKTFSTY--------------------SDNQPGVSIQVYEGE 444
                          |.|      |..|.|:                    ..:|..:.|.||..|
Zfish   545 GKHPPEKMLVKDGMRWC------TDVFDTFISADQSVALGETVKRSYTPAKPSQQVIVIHVYCSE 603

  Fly   445 RAMTKDNNALGTF--------------DLSGI-PPAPRGVPQIEVTFDLDANGILNVSAKEMSTG 494
            :...       ||              |:||. .||.|...|..:.|.       :...:.|:..
Zfish   604 KESV-------TFITDPGVRKCGSLKLDVSGTESPAARREIQTLMQFG-------DTEIRAMAVD 654

  Fly   495 KAKNITIKNDKGRLSQAEID 514
            .|.:.|:|        |.||
Zfish   655 VATSRTVK--------ASID 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	136/670 (20%)
hspa12a	NP_001417784.2	None