Protein Alignment Hsp70Bb and hspa12a.2

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001429582.1
• Gene: hspa12a.2 / 559237
• ZFINID: ZDB-GENE-061009-20
• Length: 571
• Species: Danio rerio
• Alignment Length: 604
• Identity: 128/604 - (21%)
• Similarity: 235/604 - (38%)
• Gaps: 147/604 - (24%)

  Fly     4 IGIDLGTTYSCVGV----YQHGKVEIIAN---DQGNRT--TPSYVAFTDSE--RLIGDPA----- 52
            |.||.||:||...:    .|..:..:|.|   |.|..|  ||:.:.|.:.|  :..|..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESILIPNWGVDYGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    53 KNQVAMNPRNT-VFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEI 116
            ::.|....|.: :|:..::   :..|.:|..|:    .....:||:.| .:....||.|:    :
Zfish    73 RSTVKSQARKSFLFEHFKM---ELYDKEIHRDL----MITAKNGGQMK-ALTVFSESLRY----L 125

  Fly   117 SSMVLTKMKE--TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNV------LRIINEP 173
            ....|.|:||  |.:.::...:| .|:||||.:|.:.:|..::|...|||.:      |....||
Zfish   126 KDHALEKVKENPTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFALEP 189

  Fly   174 TAAALAYGLDKNLKGERNV-----------------LIFDLGGGTFDVSI-LTIDEGSLFEVRST 220
            .||::   ..|:|..|..:                 ::.|.||||.|::: ..:::|.|.|:.:.
Zfish   190 EAASI---YCKHLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNAA 251

  Fly   221 AGDTHLGGEDFDNRLVTHLAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR-----------TLS 273
            :|: .:||:..|.:.::.|.|.|..| |.|..:..|....:|:.....||.           ||.
Zfish   252 SGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPVTLQ 315

  Fly   274 SSTEATIEIDALFEGQDFYTKVSRARFEE------------LCADLFRNTLQPVEKALNDAKMDK 326
            ...:....|::.|||      |..|.::|            ...:..:.|.:.:||..::.:::
Zfish   316 ELAKKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKITSNPELN- 373

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPD---------------------EAVAYG 370
              |..::||||......::..|:|.|....:...:.|.                     .|:.||
Zfish   374 --IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYG 436

  Fly   371 AAVQA---AILSGDQSGKI--QDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKT--FST 428
            ..:.|   .:|..|:|..:  :.....||.     .||       .:.:...:.|.:.:.  |:.
Zfish   437 IRIDAPFDKVLHKDKSNYVNSEGQTYCDVC-----FET-------FVRKGESVNCDEVRQFFFNP 489

  Fly   429 YSDNQPGVSIQVYEGERAMTK--DN---NALGTFDLSGIPPAPRGVP---QIEVTFDLDANGILN 485
            ...||.....|.:.......:  |.   ..:|.|:: |:|....|:.   ::|:.|     |...
Zfish   490 SHTNQTSAIFQFFSTNEKQVQFIDEPGVEPVGFFEV-GMPKTDGGLSREIKLEIKF-----GSTE 548

  Fly   486 VSAKEMSTGKAKNITIKND 504
            :.|........:..::|:|
Zfish   549 MKATATDVDSGETTSVKHD 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	128/604 (21%)
hspa12a.2	NP_001429582.1	None