Protein Alignment Hsp70Bb and hspa12a.3

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 611
• Identity: 124/611 - (20%)
• Similarity: 231/611 - (37%)
• Gaps: 165/611 - (27%)

  Fly     4 IGIDLGTTYSCVGV----YQHGKVEIIAN---DQGNRT--TPSYVAFTDSE--RLIG-DPAKNQV 56
            |.||.||:||...:    .|..:...|.|   :.|..|  ||:.:.|.:.|  :..| |......
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    57 AMNPRNT-----VFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEI 116
            ...|::.     :|:..::   :..|.:|..|:    .....:||:.| .:....||.|:    :
Zfish    73 RSTPKSQARKSFLFEHFKM---ELYDKEIHRDL----MITAKNGGQMK-ALTVFSESLRY----L 125

  Fly   117 SSMVLTKMKE--TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNV------LRIINEP 173
            ....|.|:||  |.:.::...:| .|:||||.:|.:.:|..::|...|||.:      |....||
Zfish   126 KDHALEKIKENTTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFALEP 189

  Fly   174 TAAALAYGLDKNLKGERNV-----------------LIFDLGGGTFDVSI-LTIDEGSLFEVRST 220
            .||::   ..|.|..|..:                 ::.|.||||.|::: ..:::|.|.|:.:.
Zfish   190 EAASI---YCKQLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNAA 251

  Fly   221 AGDTHLGGEDFDNRLVTHLAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR-----------TLS 273
            :|: .:||:..|.:.::.|.|.|..| |.|..:..|....:|:.....||.           ||.
Zfish   252 SGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPVTLQ 315

  Fly   274 SSTEATIEIDALFEGQDFYTKVSRARFEE------------LCADLFRNTLQPVEKALNDAKMDK 326
            ...:....|::.|||      |..|.::|            ...:..:.|.:.:||.:::.:::
Zfish   316 DLAKKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPELN- 373

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPD---------------------EAVAYG 370
              |..::||||......::..|:|.|....:...:.|.                     .|:.||
Zfish   374 --IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYG 436

  Fly   371 AAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTK----------- 424
            ..:.|........||...|.........:..||       .:.:...:.|.:.:
Zfish   437 IRIDAPFDKVLHKGKTSYVNSEGQTYCDVCFET-------FVRKGESVNCDEVRQFFFNPSDTNQ 494

  Fly   425 ---TFSTYSDN--------QPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVP---QIEVT 475
               ||..:|.|        :|||               .::|.|.: |:|....|:.   ::|:.
Zfish   495 TFATFQFFSTNEKQVQFIDEPGV---------------ESVGVFQV-GMPKTDGGLSREIKLEIK 543

  Fly   476 FDLDANGILNVSAKEMSTGKAKNITI 501
            |   .:..:..:|.::.:|:..::.:
Zfish   544 F---GSTEMKATATDVDSGETTSVKL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	124/611 (20%)
hspa12a.3	NP_001038346.3	ASKHA_NBD_HSP70_HSPA12	8..420	CDD:466827	98/437 (22%)