Protein Alignment Hsp70Bb and Hsc70Cb

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsc70Cb / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 200/704 - (28%)
• Similarity: 345/704 - (49%)
• Gaps: 99/704 - (14%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..||||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||..||||...|.:|||.
  Fly     1 MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDG-GKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            ..|||:|||::||.:..::...|.:|.:.| |...|.|.|.||.:.|.||::::|:.||:|||:.
  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGE---RN 191
            |.:...:.|.||..|.:|.:::|:|..||..||||||||::||.||.|||||..||...|   ||
  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195

  Fly   192 VLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPR 256
            |:..|.|..:...|.....:|.|..:.||.  ..:||.|.|..|..:.|:||:.:||.:.::|.|
  Fly   196 VIFVDFGHSSLQASACAFTKGKLKMLASTW--DQIGGRDIDLALGDYFAKEFQERYKINAKTNAR 258

  Fly   257 ALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALN 320
            |..||.|..|:.|:.:| :||:..:.|:...:..|..:.:.|::.|||||.:.:...|..::.|.
  Fly   259 ANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLA 323

  Fly   321 DAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGK 385
            ::|:....||.:.:||||:|||.|:.|:::.|: |..:.::|.||||:.|||:|.||:|  .:.:
  Fly   324 ESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMS--PAVR 385

  Fly   386 IQDVLLVDVAPLSLGI--ETAGGVMTKLIERNCRIPCKQTKTFS-TYSDNQPG-VSIQVYEGERA 446
            :::..:.|:...::.:  ::.|......||   ..|......|| ..:.|:.| .::.:..|::.
  Fly   386 VREFGVTDIQNYAVKVLWDSEGSAAPGEIE---IFPQYHASPFSRLLTINRKGPFNVSIVYGQQV 447

  Fly   447 MTKDNNALGTFDLSGIPPAPRGVPQ-IEVTFDLDANGILNVSA---------------------- 488
            ...| ..:|.:.:..:.|..||..| :::...::.|||:.:|:
  Fly   448 PYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASE 511

  Fly   489 ------------------------------------------------------KEMSTGKAKNI 499
                                                                  |:....||..:
  Fly   512 EKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATEL 576

  Fly   500 TIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGK-LDEAD 563
            .::......|..::.....:..|....|:|..:||.::||||.:|::::..::..|..: :.||:
  Fly   577 PLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAE 641

  Fly   564 KNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTKM--HQQGAGA 614
            :..::.:.|:...|| :.....|::.:..:::.|.:...||..:.  ::||..|
  Fly   642 REKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAA 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	199/703 (28%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	151/380 (40%)
Hsc70Cb	NP_001189103.1	HSPA4_like_NDB	2..381	CDD:212670	151/381 (40%)
		HSP70	3..682	CDD:278441	194/687 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464196
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740