Protein Alignment Hsp70Bb and hsc70

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 647
• Identity: 476/647 - (73%)
• Similarity: 552/647 - (85%)
• Gaps: 11/647 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:||||||||||||::|||||||||||||||||||||||||:||||||.|||||||||.|||||
Zfish     5 PAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||::|||.:..|||||||||:|||.|||:.||||||.|.|.|||:||||||||||.:|||
Zfish    70 AKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEISEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:::::|||||||||||||||||||||.|||||||||||||||||:||||||.:.|||||||||
Zfish   135 LGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.|...|||||:|||:..|.||:|||
Zfish   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:|:||.||||.::|||||||.|||||.||:||||||.||||||
Zfish   264 RTACERAKRTLSSSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDAKMDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .||||||||||||||||:|.|||:||:|::||.|||||||||||||||||||:||.|..:||:||
Zfish   329 AQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||||||||||||||.||:||..||.|||:||:|||||||||.|||||||||||||||.||.
Zfish   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||.||:
Zfish   459 FELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAD 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQSVEQAP-AGKLDEADKNSVLDKCNETIRWLDSNTTAE 585
            :|..|||..|:::|::|.|||..||:|.:||... ..|:...||.::.|||||.|.|||.|.|||
Zfish   524 QYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLDKNQTAE 588

  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGF------GGYSGPTVEEVD 641
            |:|::|:.:||.:.|:||:||::|   ||.|.||...|...||:      |..||||:||||
Zfish   589 KDEYEHQQKELEKVCNPIITKLYQ---GAGGMPGGMPGGMPGGYPGGQGSGSSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	474/645 (73%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	458/607 (75%)