Protein Alignment Hsp70Bb and F11F1.1

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001255199.1
• Gene: F11F1.1 / 3565569
• WormBaseID: WBGene00008714
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 253/606 - (41%)
• Similarity: 370/606 - (61%)
• Gaps: 11/606 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAF-TDSERLIGDPAKNQVAMNPRNTVFD 66
            :||||||||:|||..||:|:|.|:.|:.|.|||||.:|. .|.:.|||..||:.:. ...|::||
 Worm     2 SIGIDLGTTFSCVAYYQNGQVNILENENGCRTTPSVLAVGEDGDLLIGQHAKDVIG-KATNSLFD 65

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKV-VSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            .||:|||:|||..:..||..||||| ..|.|.|.:.:....:..:|:...:||::|..:|..||.
 Worm    66 VKRIIGRRYDDVLLQRDMPLWPFKVEKDDNGIPYLEIHKNEKPLKFSAVTVSSLILRCLKYNAER 130

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            .||..:..||||||||||.:||:||::|..||||.||||:|||||||:||.|.......||:||:
 Worm   131 KLGLEVKSAVITVPAYFNATQRRATEEAAEIAGLKVLRILNEPTAAAIAYSLKGQRLSRRNILIY 195

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRR 260
            |||||||||:.:.:| |....|::..|||||||:|.||.::..:.||||.::..||:.|.|||:|
 Worm   196 DLGGGTFDVAAVNVD-GPRITVKAKGGDTHLGGQDIDNIIMIKMLEEFKNRHGIDLKGNYRALKR 259

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325
            :|.|||.||.|||:|:.|.||::.|..|.||..::||..||....:|...|:..||:.:.:|.:.
 Worm   260 IRKAAEVAKITLSASSVARIELECLHLGIDFIMRISRTDFESWIENLLMATVIHVERVIREANLK 324

  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNL--SINPDEAVAYGAAVQAAILSGDQSGKIQD 388
            |.||::|||||||||||.:::::::.|. .|..:  ||:||||||||||:.||:|||.:  ::||
 Worm   325 KSQINEIVLVGGSTRIPILKNIIKQSFE-SNTRICESIHPDEAVAYGAAIMAAVLSGAE--EVQD 386

  Fly   389 VLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNA 453
            :.|:||.|:|:|::.....|:.||::....||.:.|||....|.|..:::.||||||.:...|..
 Worm   387 MRLIDVIPMSIGVQCNRDYMSVLIKKGTVFPCTKRKTFINSDDFQTSINVPVYEGERVLCSHNRQ 451

  Fly   454 LGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVN 518
            ||...|. |.|..||...:::|.::|.||||..:|.:::|.||...||..|....:|.|||.|.:
 Worm   452 LGEISLP-IQPKRRGESVVDITLEVDYNGILQATALDLNTKKAITTTILYDCCTYTQPEIDEMTS 515

  Fly   519 EAEKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTT 583
            ::|:....||..:.|.......|...:..|..:|:. .|.::....:::::.....|.||.....
 Worm   516 QSEEDRIFDEHFKMRYKQLQKSEDMAYGYKHRLEKV-KGSVEPGKFSNLMETVEREISWLSVFPK 579

  Fly   584 AEKEEFDHKMEELTRHCSPIM 604
            ....|:..:...|.....|.:
 Worm   580 VSPNEYMQRRRALRLKVYPTL 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	253/606 (42%)
F11F1.1	NP_001255199.1	ASKHA_NBD_HSP70_HSPA1-like	2..378	CDD:466878	186/378 (49%)