Protein Alignment Hsp70Bb and Hspa12b

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001381945.1
• Gene: Hspa12b / 311427
• RGDID: 1312004
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 149/650 - (22%)
• Similarity: 235/650 - (36%)
• Gaps: 204/650 - (31%)

  Fly    25 IIANDQGNRTTPSYVAF---TDSERLI-------GDPAKNQVAMNPRNT--------VFDAKRLI 71
            ::|.|.|  ||.|..||   ||.|.:.       |||.   ||.....|        :|.:....
  Rat    62 VVAIDFG--TTSSGYAFSFATDPEAIHMMRKWEGGDPG---VAHQKTPTCLLLTPEGIFHSFGYT 121

  Fly    72 GRKYD---DPKIAEDMKHW-PFKV----VSD----------GGKPKIGVEYKGESKRFAPEEISS 118
            .|.|.   ||:.|.|..:: .||:    .:|          .||..:.:|....:.||..|.
  Rat   122 ARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEH--- 183

  Fly   119 MVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPTAAA 177
             .|.:::|.:|..|.:.....|:||||.:....:|..::|.::|||      ..|.|..||.||:
  Rat   184 -ALQELREQSECMLEKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAAS 247

  Fly   178 L-----------------AYG--------LDKNLKGERNVL------------------------ 193
            :                 |.|        :|.:.:..|..|
  Rat   248 VYCRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEMQE 312

  Fly   194 -----IFDLGGGTFDVSILTIDE--GSLFEV-RSTAGDTHLGGED--FDNRLVTHLAEEFKRKYK 248
                 :.|.||||.|:::..:::  |:|.|: :::.|.....|.|  |:..|.....|:|..|:|
  Rat   313 GDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAKFK 377

  Fly   249 KDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFE------------ 301
               |..|.|...|..|.|..|||........:.|...|...|||.|......|
  Rat   378 ---RQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVK 439

  Fly   302 -----------ELCADLFRNT----LQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEF 351
                       |...:||:.|    :|.:|..|  ||.:...:..:.||||......:|..:||.
  Rat   440 WSSQGMLRMSCEAMNELFQPTVSGIIQHIEMLL--AKPEVQGVKLLFLVGGFAESAVLQHAVQEA 502

  Fly   352 FHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMT------- 409
            ...:.|.:.:..|..:   ..::.|:|.|...|    |:.|..:||:.|:    ||:.
  Rat   503 LGNRGLRVVVPHDVGL---TILKGAVLFGQAPG----VVRVRRSPLTYGV----GVLNRFVPGHH 556

  Fly   410 ---KLIERNCRIPCKQTKTFS-----------------TYSDNQPG---VSIQVY----EGERAM 447
               ||:.|:.|..|  |..|.                 :|...:||   |.|.:|    |..|.:
  Rat   557 PPEKLLVRDGRRWC--TDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFI 619

  Fly   448 T----KDNNAL-------GTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITI 501
            |    :...||       |:.:.:|..|:.|.:.......|.:    :.|:|.::||.::....|
  Rat   620 TDPGVRKCGALSLELEPEGSPENTGTSPSRREIRAAMQFGDTE----IKVTAVDVSTNRSVRAAI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	148/649 (23%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	111/481 (23%)
Hspa12b	NP_001381945.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810