Protein Alignment Hsp70Bb and hsp70.3

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_571472.2
• Gene: hsp70.3 / 30671
• ZFINID: ZDB-GENE-110713-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 642
• Identity: 479/642 - (74%)
• Similarity: 553/642 - (86%)
• Gaps: 9/642 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.||||||
Zfish     8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDA 72

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::|||.:..|||||.|||||||||||:.||:|||:|.|.|||||||||.||||.|||||
Zfish    73 KRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAEAYL 137

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |:.:|:|||||||||||||||||||||.|||||||||||||||||:||||||....|||||||||
Zfish   138 GQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLIFDL 202

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||||::| :|||::|||||||||||||||:|.|..||||||:|||:..|.|||||||
Zfish   203 GGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRRLR 266

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||::|:||||:|:||.||||.::||||||||:||||.||.||||||.||||||.
Zfish   267 TACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMDKA 331

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||||||||||||||||:|.|||:||:|:.||.|||||||||||||||||||.||.||.:||:||:
Zfish   332 QIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLLLL 396

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            |||||||||||||||||.||:||..||.|||:||:|||||||||.|||:|||||||||||.||.|
Zfish   397 DVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 461

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.||:|||.||:|
Zfish   462 ELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQEADK 526

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVEQAP-AGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586
            |..||:..|::|:::|:||||.||:|.|||... .||:.|.||..|::||||.:.||::|..|:|
Zfish   527 YKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQLADK 591

  Fly   587 EEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYS--GPTVEEVD 641
            ||::|:::||.:.|:|:::|::|.|..|.|     ||.||.|..|.|  |||:||||
Zfish   592 EEYEHQLKELEKVCNPVISKLYQGGMPAGG-----CGAQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	477/640 (75%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	309/375 (82%)
hsp70.3	NP_571472.2	PTZ00009	5..643	CDD:240227	477/640 (75%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	309/375 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820