Protein Alignment Hsp70Bb and Hsc70-3

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_061503529.1
• Gene: Hsc70-3 / 1274027
• VectorBaseID: AGAMI1_006933
• Length: 659
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 372/620 - (60%)
• Similarity: 471/620 - (75%)
• Gaps: 10/620 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            :||||||||||||||::|:|||||||||||.|||||||| |.||||||.||||:..||.||||||
Mosquito    34 VGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 98

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::.|..:..|:|..||||:....||.|.|......|.|||||||:|||.||||||||||
Mosquito    99 KRLIGREFTDHTVQHDIKLLPFKVIEKNSKPHIRVSTGQGDKVFAPEEISAMVLGKMKETAEAYL 163

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |:.:|.||:||||||||:|||||||||.||||.|:||||||||||:||||||. .||:|||:|||
Mosquito   164 GKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLVVMRIINEPTAAAIAYGLDKK-DGEKNVLVFDL 227

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:||||.| :|||.:|.|||||||||||.|::.|..:.:|:|..||:|.:.||:::||
Mosquito   228 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKMYKKKKGKDIRKDNRAVQKLR 291

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ...|:|||.||:|.:..|||::.|||.||...::||:||||..||||:|::||.|.|.||.|.|.
Mosquito   292 REVEKAKRALSASHQVRIEIESFFEGDDFSETLTRAKFEELNMDLFRSTMKPVHKVLEDADMTKN 356

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            .:.:||||||||||||||.|::|||:||..:..|||||||||||||||.:|||:|.  ...::|:
Mosquito   357 DVDEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEQD--TDAIVLL 419

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||.||::||||.||||||||.||..||.|:::.|||.||||..|:||||||||.|||||:.||.|
Mosquito   420 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 484

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:||||||||:|||||:|::||||||.|||::..||..:.|.|.||:.||:..:|:||:.:||:
Mosquito   485 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNREKIVITNDQNRLTPDDIERMIKDAER 549

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQ--SVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAE 585
            :||:|:|.::|:.:||.||||.:::|.  |.:......:.:.||..:.:..:|.|:|||.|...|
Mosquito   550 FADDDKKLKERVEARNELESYAYSLKNQLSSKDKLGASVSDDDKAKMEEAIDEKIKWLDENQDTE 614

  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGA---AGG 617
            .||:..:.:||.....||:||::....||   |||
Mosquito   615 AEEYKKQKKELEDIVQPIITKLYASSGGAPPPAGG 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	372/620 (60%)
Hsc70-3	XP_061503529.1	None