Protein Alignment Hsp70Bb and hspa12a

DIOPT Version :9

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_002941887.2
• Gene: hspa12a / 100489323
• XenbaseID: XB-GENE-959285
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 140/652 - (21%)
• Similarity: 229/652 - (35%)
• Gaps: 197/652 - (30%)

  Fly     4 IGIDLGTTYS-----------CVGVYQHGKVEIIANDQG--NRTTPSYVAFTDSERLIGDPAKNQ 55
            :.||.|||.|           |:.:.:..:    ..|.|  |:.||:.:.      |:.|...:.
 Frog    56 VAIDFGTTSSGYAYSFSKEPECIHIMRRWE----GGDPGVSNQKTPTTML------LMPDRKFHS 110

  Fly    56 VAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHW----PFKVVSDGGKPKIGVEYK---GESKRFAP 113
            .....|:...|.         ||   .:.|||    .||:... ....:.:|.:   ...||...
 Frog   111 FGFAARDFYHDL---------DP---SESKHWLYFEKFKMKLH-SSTDLTMETELTAANGKRVKA 162

  Fly   114 EEISSMVLTKMKETAEAYL----GESITDA----VITVPAYFNDSQRQATKDAGHIAGL------ 164
            .||.:..|...||.|...|    |..:..|    ||||||.:....:|..:.|.:.||:
 Frog   163 LEIFAYALQYFKEQALKELSDQAGSEMDSAEVRWVITVPAIWKQPAKQFMRQAAYKAGMATPENP 227

  Fly   165 NVLRIINEPTAA------------------ALAYGLD-----KNL-------------------- 186
            ..|.|..||..|                  |...|:.     |:|
 Frog   228 EQLIIALEPEGASIYCRKLRLHQMIDLSSKAAINGISPTDPAKDLARRNRQSRTFLVENVIGELW 292

  Fly   187 ----KGERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDNRLVTHLAEE 242
                :|:|.|:: |.||||.|:::  :.:.||.|.|:...:|..:  ||.: :|:..|.....::
 Frog   293 SELEEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSLGVDYEFEKLLCKIFGDD 356

  Fly   243 FKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV-----------S 296
            |...:|.   ..|.|...|..|.|..||..:......:.|...|...|:|.|.           |
 Frog   357 FIDTFKV---KRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKS 418

  Fly   297 RARFEELCAD------------LFRNTLQPVEKALND--AKMDKGQIHDIVLVGGSTRIPKVQSL 347
            ...|.:..:.            ||:.|:.|:.:.|.:  .|.:...:..:.||||....|.:|..
 Frog   419 NVDFVKWSSQGMLRMNPDAMNALFKPTIDPIIQHLTNLFQKPEVAGVKFLFLVGGFAESPLLQQA 483

  Fly   348 LQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDV--APLSLGIETAGGVMTK 410
            :|:.| |....:.|..|..:   ..::.|:|.|      .|..|:.|  :||:.|:    ||:.:
 Frog   484 VQQAF-GDQCRVIIPHDVGL---TILKGAVLFG------LDPALIKVRRSPLTYGV----GVLNR 534

  Fly   411 LIE--------------RNC------------RIPCKQT--KTFSTYSDNQPGVSIQVYEGERAM 447
            .:|              |.|            .:...:|  ::::....:|..:.|.:|..|:
 Frog   535 YVEGKHPPEKLLLKDGTRWCTDVFDKFILADQSVALGETVKRSYTPAKQSQLIIIIHIYSSEQ-- 597

  Fly   448 TKDNNAL--------GT--FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIK 502
             .|.|.:        ||  .||:|...||  ||.......:...|...:.|..:....:||:.:.
 Frog   598 -DDANFITDKGVRKCGTLRLDLTGPESAP--VPSRREIQTIMQFGDTEIKATAVDVATSKNVKVS 659

  Fly   503 ND 504
            .|
 Frog   660 ID 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	140/652 (21%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	106/485 (22%)
hspa12a	XP_002941887.2	HSPA12A_like_NBD	54..513	CDD:212685	108/493 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910