Protein Alignment Hsp70Bb and hspa1a

DIOPT Version :10

• Sequence 1: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_012823021.1
• Gene: hspa1a / 100488052
• XenbaseID: XB-GENE-5842877
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 480/647 - (74%)
• Similarity: 555/647 - (85%)
• Gaps: 10/647 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:|||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.|||||
 Frog     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||::|||.:..|||||||.|::|||:||:.||||||:|.|..||:||||||||||.:|||
 Frog    70 AKRLIGRRFDDPVVQSDMKHWPFTVINDGGRPKVQVEYKGEAKTFYAEEVSSMVLTKMKEISEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||::||:|||||||||||||||||||||.|:|||||||||||||||:||||||.:.|||||||||
 Frog   135 LGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.|...|||||:|||:..|.||:|||
 Frog   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFVGEFKRKHKKDITENKRAIRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:|:||.||||.::|||||||.|||||.||:||||||.||||||
 Frog   264 RTACERAKRTLSSSTQASIEIDSLYEGIDFYTSLTRARFEELNADLFRGTLEPVEKALRDAKMDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .||||||||||||||||:|.|||:||:|:.||.||||||||||||||||||||||:|..:||:||
 Frog   329 AQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||||||||||||||.||:||..||.|||:||:|||||||||.|||:|||||||||||.||.
 Frog   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|:|||||||||||||||||:|||||:||||.:.||||...|||.|||||||:.||:|||.||:
 Frog   459 FELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEEIERMVQEAD 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQSVE-QAPAGKLDEADKNSVLDKCNETIRWLDSNTTAE 585
            :|..|||..|::|:::|:|||..||:|.:|| :....|:...||..:||||||.|.|||.|..||
 Frog   524 RYKAEDEVQREKISAKNSLESLAFNMKSTVEDEKLKDKISPEDKQKILDKCNEVISWLDRNQMAE 588

  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGA------NCGQQAGGFGGYSGPTVEEVD 641
            |||::|:.:||...|:||:||:: ||||.||.||.      ..|..||| ||.||||:||||
 Frog   589 KEEYEHQQKELQNLCNPIITKLY-QGAGGAGMPGGMPGGFPGAGAGAGG-GGSSGPTIEEVD 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	478/645 (74%)
hspa1a	XP_012823021.1	PTZ00009	1..612	CDD:240227	458/608 (75%)