Protein Alignment Hsp70Aa and SSC1

DIOPT Version :9

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_012579.1
• Gene: SSC1 / 853503
• SGDID: S000003806
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 309/630 - (49%)
• Similarity: 425/630 - (67%)
• Gaps: 27/630 - (4%)

  Fly     4 IGIDLGTTYSCVGVYQHGKV-EIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||.|.|.:.: ||| :||.|.:|:|||||.|||| :.|||:|.|||.|..:||.||:|.
Yeast    33 IGIDLGTTNSAVAIME-GKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFA 96

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .||||||:::|.::..|:|..|:|:|  |:|   ...||.:|::  ::|.:|...||.|||||||
Yeast    97 TKRLIGRRFEDAEVQRDIKQVPYKIVKHSNG---DAWVEARGQT--YSPAQIGGFVLNKMKETAE 156

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLI 194
            ||||:.:.:||:||||||||||||||||||.|.||||||::||||||||||||:|:  ..:.|.:
Yeast   157 AYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKS--DSKVVAV 219

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALR 259
            |||||||||:|||.||.| :|||:||.|||||||||||..|:..:...||.:...||.::..|::
Yeast   220 FDLGGGTFDISILDIDNG-VFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQ 283

  Fly   260 RLRTAAERAKRTLSS--STEATIE-IDALFEG-QDFYTKVSRARFEELCADLFRNTLQPVEKALN 320
            |:|.|||:||..|||  |||..:. |.|...| :....|.|||:||.|.|.|.:.|:.||:|||.
Yeast   284 RIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALK 348

  Fly   321 DAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGK 385
            ||.:....|.:::||||.:|:|||...::..| ||:.:.::|||||||.|||||.|:|||:
Yeast   349 DAGLSTSDISEVLLVGGMSRMPKVVETVKSLF-GKDPSKAVNPDEAVAIGAAVQGAVLSGE---- 408

  Fly   386 IQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKD 450
            :.||||:||.||||||||.|||.|:||.||..||.|:::.|||.|..|..|.|:|::|||.:.:|
Yeast   409 VTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRD 473

  Fly   451 NNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDR 515
            |..:|.|.|:||||||:||||||||||:||:||:||||::.:|.|..:||:....| ||:.||::
Yeast   474 NKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSG-LSENEIEQ 537

  Fly   516 MVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDK---CNDTIRW 577
            |||:|||:..:||..:|.|.:.|..:....:.:.::::. .||:|:|:...|.|:   ..:.:..
Yeast   538 MVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEF-EGKVDKAEAQKVRDQITSLKELVAR 601

  Fly   578 LDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGAN 622
            :........||...|.|||......:..::::..:.......|.|
Yeast   602 VQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNN 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	309/630 (49%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	207/382 (54%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	307/615 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810