Protein Alignment Hsp70Aa and SSQ1

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_013473.1
• Gene: SSQ1 / 851084
• SGDID: S000004361
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 622
• Identity: 266/622 - (42%)
• Similarity: 383/622 - (61%)
• Gaps: 63/622 - (10%)

  Fly     4 IGIDLGTTYSCVGVYQHG----KVEIIANDQGNRTTPSYVAF---------TDSERLIGDPAKNQ 55
            ||||||||.|.|...:..    ...||.||:|.|||||.|||         ...:.|:|..||.|
Yeast    31 IGIDLGTTNSAVAYIRDSNDKKSATIIENDEGQRTTPSIVAFDVKSSPQNKDQMKTLVGMAAKRQ 95

  Fly    56 VAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRF--APEEISS 118
            .|:|..||.|..||||||.::|.::..||...|:|:|.....   |..|...|...  :|.:|:|
Yeast    96 NAINSENTFFATKRLIGRAFNDKEVQRDMAVMPYKIVKCESN---GQAYLSTSNGLIQSPSQIAS 157

  Fly   119 MVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLD 183
            ::|..:|:|:|.||||.:..|||||||||||||||||||||.:|||||||:|||||||||::|:|
Yeast   158 ILLKYLKQTSEEYLGEKVNLAVITVPAYFNDSQRQATKDAGKLAGLNVLRVINEPTAAALSFGID 222

  Fly   184 KNLKGERN---VLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKR 245
                .:||   :.::||||||||:|||.|::| :||||:|.||||||||||||.:|.::.|.|..
Yeast   223 ----DKRNNGLIAVYDLGGGTFDISILDIEDG-VFEVRATNGDTHLGGEDFDNVIVNYIIDTFIH 282

  Fly   246 K----YKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCAD 306
            :    .::::..|...::||:..:||||..||...:..||:..:::.:.....::....:.:...
Yeast   283 ENPEITREEITKNRETMQRLKDVSERAKIDLSHVKKTFIELPFVYKSKHLRVPMTEEELDNMTLS 347

  Fly   307 LFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGA 371
            |...|:.||::||.||.::...|.:::||||.||:||::|:::|.| ||:.|.|:||||.||.||
Yeast   348 LINRTIPPVKQALKDADIEPEDIDEVILVGGMTRMPKIRSVVKDLF-GKSPNSSVNPDETVALGA 411

  Fly   372 AVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGV 436
            |:|..||||:    |::|||:||.||:|||||.||..:.||.||..:|.|:|:.|||..|.|.||
Yeast   412 AIQGGILSGE----IKNVLLLDVTPLTLGIETFGGAFSPLIPRNTTVPVKKTEIFSTGVDGQAGV 472

  Fly   437 SIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITI 501
            .|:|::|||.:.::|..:|...|:||.|.|:|:|||.||||:||:||:||||.|.|:||.::||:
Yeast   473 DIKVFQGERGLVRNNKLIGDLKLTGITPLPKGIPQIYVTFDIDADGIINVSAAEKSSGKQQSITV 537

  Fly   502 KNDKGRLSQAEIDRMVNEAEKYADEDEKHRQR------------------------ITSRNALES 542
            ..:.| ||:.||.:::.||.....:|...|||                        |:|.....:
Yeast   538 IPNSG-LSEEEIAKLIEEANANRAQDNLIRQRLELISKADIMISDTENLFKRYEKLISSEKEYSN 601

  Fly   543 YVFNVK---QAVEQAPAGKLDEADKNSVLDKCNDTIR 576
            .|.::|   ||::...|.:.|.:...:.:.|..|.::
Yeast   602 IVEDIKALRQAIKNFKANENDMSIDVNGIKKATDALQ 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	266/622 (43%)
SSQ1	NP_013473.1	ASKHA_ATPase-like	29..656	CDD:483947	266/622 (43%)