Protein Alignment Hsp70Aa and hspa1b

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 641
• Identity: 467/641 - (72%)
• Similarity: 540/641 - (84%)
• Gaps: 8/641 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.||:|||
Zfish     6 SIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTIFDA 70

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            |||||||:||..:..|||.|||||:|:.||||:.||||||:|.|.|||||||||.||:|.|||||
Zfish    71 KRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREIAEAYL 135

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..:.:|||||||||||||||||||||.|||||||||||||||||:||||||..|||||||||||
Zfish   136 GHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNVLIFDL 200

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||||::| :|||::|||||||||||||||:|.|..:|||||:|||:..|.||:||||
Zfish   201 GGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRAVRRLR 264

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||::|:||||:||||.||||.::|||||||.|:|||.||.||||||.||||||.
Zfish   265 TACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDAKMDKS 329

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||.|||||||||||||:|.||||||:|::||.|||||||||||||||||||.||.|..:||:||:
Zfish   330 QIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQDLLLL 394

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTF 457
            |||||||||||||||||.||:||..||.|||:.||||:||||||.|||:|||||||||||.||.|
Zfish   395 DVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 459

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||.:|||
Zfish   460 DLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMVQDAEK 524

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQAVE-QAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAEK 586
            |..|||..|::|.::||||||.|::|..|| :...||:.|.||..::|||.:.:.||::|..|||
Zfish   525 YKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENNQLAEK 589

  Fly   587 EEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            ||::|..:||...|:||:::::|.||     .|...||.||..... .|||:||||
Zfish   590 EEYEHHQKELESVCNPIISRLYQGGA-----PPAGGCGFQAQPESS-QGPTIEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	465/639 (73%)
hspa1b	NP_001093532.1	PTZ00009	1..639	CDD:240227	465/639 (73%)