Protein Alignment Hsp70Aa and hyou1

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001263614.1
• Gene: hyou1 / 779444
• XenbaseID: XB-GENE-921821
• Length: 985
• Species: Xenopus tropicalis
• Alignment Length: 647
• Identity: 193/647 - (29%)
• Similarity: 309/647 - (47%)
• Gaps: 92/647 - (14%)

  Fly     4 IGIDLGTTYSCVGVYQHG-KVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :.:|:|:.:..:.:.:.| .:||:.|.:..|.||..:|..::|||.||.|......||:.|....
 Frog    36 MSVDMGSEWMKIAIVKPGVPMEIVLNKESRRKTPVAIALKENERLFGDSALGMAVKNPKVTFRYF 100

  Fly    68 KRLIGRKYDDPKIAEDMKHWP-FKVVSDGGKPKIGVEYK-GESKRFAPEEISSMVLTKMKETAEA 130
            :.|:|::.|:|.:......:| :::|.|  :.:..|.:| .|...::|||:..|:|...:..||.
 Frog   101 QDLLGKRADNPHVKAFEARFPEYQLVKD--EHRETVLFKLSEELTYSPEELLGMMLNYSRSLAEE 163

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGL----DKNLKGERN 191
            :..:.:.|.||||||:||.::|:|...|..::.|.||::||:.||.||.||:    |.|...: |
 Frog   164 FAEQPVKDVVITVPAFFNQAERRAVLQAAQLSDLKVLQLINDNTAVALNYGVFRRKDINATAQ-N 227

  Fly   192 VLIFDLGGGTFDVSILTI------DEG--SLFEVRSTAGDTHLGGEDFDNRLVTHLADEF--KRK 246
            ::.:::|..:...:|:|.      |.|  ...::|....|..|||.:.|.||..|||..|  ::|
 Frog   228 IMFYEMGSRSTICTIVTYQSVKTKDSGMQPQLQIRGVGFDRTLGGIEMDLRLRDHLAKLFNEQKK 292

  Fly   247 YKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNT 311
            .|||:|.|.||:.:|...|.|.|..||::.:...:|:.|.:..||..||:|...|:||||||...
 Frog   293 SKKDVRENQRAMSKLLKEANRVKTILSANNDHMAQIEGLMDDIDFKAKVTRQELEDLCADLFNRV 357

  Fly   312 LQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAA 376
            ..||:.||:.|:|...:|..::||||:||:||||.||......:.|..:||.|||.|.||..|||
 Frog   358 SAPVQHALSSAEMKMEEIDQVILVGGATRVPKVQELLLKVVGKEELGKNINADEAAAMGAVYQAA 422

  Fly   377 ILSGDQSGKIQDVLLVDVAPLSLGIETAGGV----MTKLIERNCRI--------PCKQTKTFSTY 429
            .||  ::.|::..::.|.|...:.:|....|    .:|.::.|.||        |.::..||:.|
 Frog   423 ALS--KAFKVKPFIVRDAAIFPIQVEFTREVEEEDHSKSLKHNKRILFQRLAPYPQRKVITFNRY 485

  Fly   430 ADNQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEM--- 491
            .||   .:..:..|              |||.:.|.           ||...|.||::..::
 Frog   486 TDN---FAFSINYG--------------DLSYLGPD-----------DLKVFGSLNLTTVKLNGV 522

  Fly   492 --STGKAKNITIKNDKGRLSQAE-----IDRMVNEAEKYADEDEKHRQRITSRNALESYVF---- 545
              |..|..:...|..|...:..|     :||:....|...||..:....:|......|.:|
 Frog   523 GESFQKRSDYESKGIKAHFNMDESGLLTLDRVEAVFETVVDEKPEQESTLTKLGNTISSLFGGGS 587

  Fly   546 -------NVKQAVEQ-----APAGKLDEADKNSVLDKCNDTIRWLDSNTTAEKEEFDHKLEE 595
                   |...:|::     ....|.:|.:.....||..|.    :..|||..||.:.|.||
 Frog   588 SVPETKENATDSVQEEDEVPTEPTKEEEQESADAADKQKDK----EKGTTATNEEEEGKKEE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	193/647 (30%)
hyou1	NP_001263614.1	ASKHA_NBD_HSP70_HYOU1	34..422	CDD:466828	136/388 (35%)
		PTZ00121	<602..806	CDD:173412	13/48 (27%)