Protein Alignment Hsp70Aa and hspa12a

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001417784.2
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 670
• Species: Danio rerio
• Alignment Length: 682
• Identity: 140/682 - (20%)
• Similarity: 228/682 - (33%)
• Gaps: 250/682 - (36%)

  Fly    19 QHGKVEIIANDQGNRTTPSYVAFTDSERLI--------GDP-AKNQ-----VAMNPRNTVFDAKR 69
            :|..|.::|.|.|..::....|||.....|        ||| ..||     :.:.| :..|.:..
Zfish    49 RHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTP-DKKFHSFG 112

  Fly    70 LIGRKYDDPKIAEDMKHW----PFKV---------------VSDGGKPKIGVEYKGESKRFAPEE 115
            ...|.:.......:.|.|    .||:               .::|.|.| .::....:..|..|:
Zfish   113 YAARDFYHDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK-ALDIFAYALAFFKEQ 176

  Fly   116 ISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPT 174
                .|.::.:.|.|....:....||||||.:....:|..::|.:.|.|      :.|.|..||.
Zfish   177 ----ALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIALEPE 237

  Fly   175 AAAL--------------------AYGLDKN---------------------------------- 185
            ||::                    .|....|
Zfish   238 AASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELWSEL 302

  Fly   186 LKGERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH---------------LGGEDFDN 233
            .:|:|.|:: |.||||.|:::  :.:.||.|.|:...:|..:               :.|:||
Zfish   303 AEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKLLCKIFGQDF-- 364

  Fly   234 RLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV--- 295
                  .|:||.|       .|.|...|..|.|..||..:......:.|:..|...|:|.|.
Zfish   365 ------IDQFKIK-------RPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGH 416

  Fly   296 --------SRARFEELCAD------------LFRNTLQPVEKALNDAKMDKGQIHDI---VLVGG 337
                    |...|.:..:.            ||:.|:..:.:.|.:. .|:.::.||   .||||
Zfish   417 SVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGG 480

  Fly   338 STRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGI 401
            ....|.:|..:|:...|:: .:.|..|..:   ..::.|:|.| |.|     ::.|..:||:.|:
Zfish   481 FAESPLLQQAVQNMLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS-----IIKVRRSPLTYGV 536

  Fly   402 ETAGGVMTKLIE--------------RNCRIPCKQTKTFSTY--AD------------------N 432
                ||:.:.:|              |.|      |..|.|:  ||                  :
Zfish   537 ----GVLNRFVEGKHPPEKMLVKDGMRWC------TDVFDTFISADQSVALGETVKRSYTPAKPS 591

  Fly   433 QPGVSIQVYEGERAMTKDNNALGTF--------------DLSGI-PPAPRGVPQIEVTFDLDANG 482
            |..:.|.||..|:...       ||              |:||. .||.|...|..:.|.
Zfish   592 QQVIVIHVYCSEKESV-------TFITDPGVRKCGSLKLDVSGTESPAARREIQTLMQFG----- 644

  Fly   483 ILNVSAKEMSTGKAKNITIKNDKGRLSQAEID 514
              :...:.|:...|.:.|:|        |.||
Zfish   645 --DTEIRAMAVDVATSRTVK--------ASID 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	140/682 (21%)
hspa12a	NP_001417784.2	None