Protein Alignment Hsp70Aa and hspa9

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_958483.2
• Gene: hspa9 / 373085
• ZFINID: ZDB-GENE-030828-12
• Length: 682
• Species: Danio rerio
• Alignment Length: 637
• Identity: 312/637 - (48%)
• Similarity: 422/637 - (66%)
• Gaps: 32/637 - (5%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            ||||||||.|||.|......:::.|.:|.|||||.|||| |.|||:|.|||.|...||.||::..
Zfish    59 IGIDLGTTNSCVAVMDGKNAKVLENAEGARTTPSVVAFTSDGERLVGMPAKRQAVTNPNNTLYAT 123

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ||||||::||.::.:|:|:.|:|:|  |:|   ...:|..|  |.::|.:..:.:|.|||||||:
Zfish   124 KRLIGRRFDDAEVQKDLKNVPYKIVRASNG---DAWLEVHG--KMYSPSQAGAFILIKMKETAES 183

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            |||:|:.:||:||||||||||||||||||.||||||||:|||||||||||||||.  .::.:.::
Zfish   184 YLGQSVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGLDKT--QDKIIAVY 246

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260
            ||||||||:|:|.|.:| :|||:||.|||.|||||||..|:.|:..|||::...||..:..||:|
Zfish   247 DLGGGTFDISVLEIQKG-VFEVKSTNGDTFLGGEDFDQHLLRHIVKEFKKESGVDLMKDNMALQR 310

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEG----QDFYTKVSRARFEELCADLFRNTLQPVEKALND 321
            :|.|||:||..||||.:..|.:..|...    :....|::|::||.:.|||.|.|:.|.:||:.|
Zfish   311 VREAAEKAKCELSSSLQTDINLPYLTMDASGPKHLNMKLTRSQFEGIVADLIRRTVAPCQKAMQD 375

  Fly   322 AKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKI 386
            |::.|..|.:::||||.||:||||..:||.| |:..:.|:|||||||.|||:|..:|:||    :
Zfish   376 AEVSKSDIGEVLLVGGMTRMPKVQQTVQDLF-GRAPSKSVNPDEAVAIGAAIQGGVLAGD----V 435

  Fly   387 QDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDN 451
            .||||:||.||||||||.|||.||||.||..||.|:::.|||.||.|..|.|:|.:|||.|..||
Zfish   436 TDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMATDN 500

  Fly   452 NALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRM 516
            ..||.|.|.|||||.|||||||||||:|||||::||||:..||:.:.|.|:: .|.||:.:|:.|
Zfish   501 KVLGQFTLVGIPPALRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQS-SGGLSKDDIENM 564

  Fly   517 VNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVE----QAPAGKLDEADK-NSVLDKCNDTIR 576
            |..|||||:||.:.:.|:.:.|..|..|.:.:..:|    |.||   ||.:| ...:.|..:.:.
Zfish   565 VKNAEKYAEEDRRRKDRVEAVNMAEGIVHDTESKMEEFKDQLPA---DECNKLKEEISKVRELLS 626

  Fly   577 WLDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAG 628
            ..|:.|   .|........|.:....:....:::.|....|..|::...:||
Zfish   627 RKDTET---GENIKQAATSLQQASLKLFEMAYKKMASEREGSSGSSSSGEAG 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	312/637 (49%)
hspa9	NP_958483.2	dnaK	56..659	CDD:234715	307/619 (50%)