Protein Alignment Hsp70Aa and Hsc70-3

DIOPT Version :9

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001285139.1
• Gene: Hsc70-3 / 32133
• FlyBaseID: FBgn0001218
• Length: 656
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 378/627 - (60%)
• Similarity: 480/627 - (76%)
• Gaps: 11/627 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            |||||||||||||||::|:|||||||||||.|||||||| |.||||||.||||:..||.||||||
  Fly    32 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDA 96

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::.|..:..|:|.:|||||....||.|.|:....:|.|||||||:|||.||||||||||
  Fly    97 KRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYL 161

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |:.:|.||:||||||||:|||||||||.||||.|:||||||||||:||||||. :||:|||:|||
  Fly   162 GKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK-EGEKNVLVFDL 225

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:||||.| :|||.:|.|||||||||||.|::.|....:|:|..||:|.:.||:::||
  Fly   226 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLR 289

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ...|:|||.||.|.:..|||::.|||.||...::||:||||..||||:||:||:|.|.||.|:|.
  Fly   290 REVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            .:|:||||||||||||||.|::|||.||..:..|||||||||||||||.:|||:|.  ...::|:
  Fly   355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQD--TDAIVLL 417

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||.||::||||.||||||||.||..||.|:::.|||.:|||..|:||||||||.|||||:.||.|
  Fly   418 DVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKF 482

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:||||||||:|||||:|::||||||.|||::..||..:.|.|.||:.||:..:||||:.:|||
  Fly   483 DLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEK 547

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQAV--EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            :||||:|.::|:.|||.||||.:::|..:  :.....||.:.:||.:....:::|:||:.|..|:
  Fly   548 FADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDAD 612

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQA 627
            .||:..:.::|.....|::.|::|   ||| |.|....|..|
  Fly   613 PEEYKKQKKDLEAIVQPVIAKLYQ---GAG-GAPPPEGGDDA 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	378/627 (60%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	253/375 (67%)
Hsc70-3	NP_001285139.1	HSPA5-like_NBD	29..403	CDD:212681	252/372 (68%)
		PTZ00009	32..643	CDD:240227	375/618 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464239
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.740