Protein Alignment Hsp70Aa and Hsc70Cb

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_061509666.1
• Gene: Hsc70Cb / 1275989
• VectorBaseID: AGAMI1_015163
• Length: 843
• Species: Anopheles gambiae
• Alignment Length: 710
• Identity: 219/710 - (30%)
• Similarity: 354/710 - (49%)
• Gaps: 114/710 - (16%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..||||.|...|.|.|.:.|.:|.||||...|.|||:|||....|::|..||||...|..||:.
Mosquito     1 MSVIGIDFGNDSSYVAVAKAGGIETIANDYSLRATPSFVAFAGRNRVLGVAAKNQQVTNMNNTIG 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPF--KVVSDGGKPKIG--VEYKGESKRFAPEEISSMVLTKMKE 126
            :.|.|:|||:|||:..|:::..|:  :.:.|||   ||  |.|..|...|:||:|::|:.||:||
Mosquito    66 NFKELLGRKFDDPRAQEELRSLPYHTEALQDGG---IGIRVNYLDEEHVFSPEQITAMLFTKLKE 127

  Fly   127 TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN-----L 186
            .|...|...|.|.|||||:||.::||||..||.:|:||||||::||.||.||:||..|.     .
Mosquito   128 DAFKELKTQINDCVITVPSYFTNAQRQALLDAANISGLNVLRLMNETTATALSYGFYKQDLPAPE 192

  Fly   187 KGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDL 251
            :..|||:..|.|..:..||.....:|:| ::.::..|: :||.|||..|.||...||:.|||.|.
Mosquito   193 EKPRNVIFVDCGHASLQVSACAFHKGNL-KMLASCSDS-VGGRDFDLVLATHFNKEFQTKYKIDA 255

  Fly   252 RSNPRALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPV 315
            .|..||..||....|:.|:.:| :||:..:.|:......|.::.:.|:..|||.:.||:.....:
Mosquito   256 SSKKRAFLRLMAEVEKLKKNMSANSTKLPLNIECFMNEIDVHSSMQRSEMEELSSHLFKRIETTM 320

  Fly   316 EKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            .|.|.|:|:...:||.:.:||||:|||.::.|::..| ||..:.::|.||||:.|||:|.||||
Mosquito   321 RKLLLDSKLALEEIHSVEIVGGSSRIPAIKHLIEQIF-GKPASTTLNQDEAVSRGAALQCAILS- 383

  Fly   381 DQSGKIQDVLLVDVAPLSLGI---ETAGGVMTKLIERNCRIP-CKQTKTFSTYADNQPGVSIQVY 441
             .:.::::....||....:.|   :|.|....|:.|:....| |:    ..|....:| ::|:|:
Mosquito   384 -PAVRVREFSCTDVQAYPVLISWTDTDGPHEMKVFEQYHAAPFCR----LLTVHRKEP-MTIKVH 442

  Fly   442 EGERAMTKDNNALGTFDLSGIPPAPRGVPQ-IEVTFDLDANGILNVSAKEM-------------- 491
            ....::...:..:||:.:.||.|...|..| ::|...::.|||:.||:..|
Mosquito   443 YEPNSIPYPDPFIGTYHVKGIKPDANGEAQEVKVKVRINNNGIITVSSATMYERKESEEPSSPTP 507

  Fly   492 -------STGKAKNITIKND--------------------------------------------- 504
                   .||.|...:.:.|
Mosquito   508 TSNGDQQKTGDANQSSPQGDESGKVGEPMDIQEGSDDEHPKKDSKPNDSSGEGWTQRVTRWFTSD 572

  Fly   505 -KGRLSQAEIDRMVN---------EAEKYADE-------DEKHRQRITSRNALESYVFNVKQAVE 552
             |.:::..:::..::         |..||.:|       |.:.::||.:|||||..|:.:::.::
Mosquito   573 KKKKVTTKQVELTIDSNTHGFVHTELCKYFEEEMKMIANDRQEKERIDARNALEEQVYEIREKIQ 637

  Fly   553 QAPA--GKLDEADKNSVLDKCNDTIRWL-DSNTTAEKEEFDHKLEELTRHCSPIMTKMHQ 609
            :..|  ..:|..|.:::..:..:|..|| :...:.||..:..:||::.....|:..:..:
Mosquito   638 EDGALHDYIDPQDASAICRELEETENWLYEEGESCEKGVYKERLEKMRAKIDPVRNRCEE 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	218/709 (31%)
Hsc70Cb	XP_061509666.1	None