Protein Alignment Hsp60B and CCT2

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_012124.1
• Gene: CCT2 / 854664
• SGDID: S000001404
• Length: 527
• Species: Saccharomyces cerevisiae
• Alignment Length: 556
• Identity: 127/556 - (22%)
• Similarity: 228/556 - (41%)
• Gaps: 116/556 - (20%)

  Fly    37 GVDILADAVAVTMGPKGRSVIVERPWTSP-KITKDGFTVARSIALKDQHMNLGAKLVQDVADNTN 100
            |...:.|.|..|:||||...:::...::. .:|.||.|:.:||.|.    |..||::.:::...:
Yeast    25 GAIAVGDLVKSTLGPKGMDKLLQSASSNTCMVTNDGATILKSIPLD----NPAAKVLVNISKVQD 85

  Fly   101 ESAGDGTTTATVLARAIAKEGFNQITMG-ANPVEIRRGVMLAVDVVKDKLKEMSKAVET------ 158
            :..|||||:.|||:..:.:|....|... .:|..|..|..||.....|.|.:  .||:.
Yeast    86 DEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAALDALTK--AAVDNSHDKTM 148

  Fly   159 -REEIQQVA--TLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNI--IQGLRFDNGYV 218
             ||::..:|  |||:       :::.:..|......|..:   .|||...|:  ||.::...|.:
Yeast   149 FREDLIHIAKTTLSS-------KILSQDKDHFAELATNAI---LRLKGSTNLEHIQIIKILGGKL 203

  Fly   219 SPFFVNSS---------------KGSKVEFANALVMISLKKITG----------LSQIVKGLEQS 258
            |..|::..               :.:|:..||..:.....||.|          |:|:.|...:.
Yeast   204 SDSFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFKVDSTAKLAQLEKAEREK 268

  Fly   259 LRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDI 323
            ::.:     ||: ||...:|..:                     .::||.|..    ..:| .|:
Yeast   269 MKNK-----IAK-ISKFGINTFI---------------------NRQLIYDYP----EQLF-TDL 301

  Fly   324 NYSKMEEAKLEDLGQV-----GEAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRD 383
            ..:.:|.|..|.:.::     ||.|    ||.....|.|.|..:: |::|.  |.|:..
Yeast   302 GINSIEHADFEGVERLALVTGGEVV----STFDEPSKCKLGECDV-IEEIM--LGEQPF------ 353

  Fly   384 RLRQRLSALTKGVA-VLHIGGGSEVEVNEKKDRVVDALNA-TRAAIEEGIVPGGGTAFLRCIPYL 446
               .:.|....|.| .:.:.|.::..::|.:..:.|||:. ::...|...|.|||.|.: .:...
Yeast   354 ---LKFSGCKAGEACTIVLRGATDQTLDEAERSLHDALSVLSQTTKETRTVLGGGCAEM-VMSKA 414

  Fly   447 QELKTESADLQK--GVDIVCNALRMPCQTIAQNAGVDGPMVVAK----VLNGSEDYGYDAMGDEY 505
            .:.:.::.|.:|  .|:....|||.....:|.|||.|...:|:|    :.||....|.|......
Yeast   415 VDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRSSIYNGISTSGLDLNNGTI 479

  Fly   506 CRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVI 541
            ..:.:.||::..|:.|..::.|:..|.:|...:.:|
Yeast   480 ADMRQLGIVESYKLKRAVVSSASEAAEVLLRVDNII 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	127/556 (23%)
		GroEL	22..543	CDD:239460	127/556 (23%)
CCT2	NP_012124.1	TCP1_beta	5..520	CDD:239452	127/556 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810