Protein Alignment Hsp60B and CCT5

DIOPT Version :10

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_012598.1
• Gene: CCT5 / 853527
• SGDID: S000003825
• Length: 562
• Species: Saccharomyces cerevisiae
• Alignment Length: 577
• Identity: 130/577 - (22%)
• Similarity: 231/577 - (40%)
• Gaps: 142/577 - (24%)

  Fly    41 LADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGD 105
            :|..:..::||:|...|:..|.....||.||.|:...:.|.::.    |||:..::.:.::..||
Yeast    57 VASIIKTSLGPRGLDKILISPDGEITITNDGATILSQMELDNEI----AKLLVQLSKSQDDEIGD 117

  Fly   106 GTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVATLSA 170
            |||...|||.|:..:....|..|.:|::|..|...|..:.      :||..||.::|      ||
Yeast   118 GTTGVVVLASALLDQALELIQKGIHPIKIANGFDEAAKLA------ISKLEETCDDI------SA 170

  Fly   171 NGDTEIGR--LIGEATDKVGPRGTITVKDGKRLKD-----ELNIIQGLRFDNGYVSPFFVNSSKG 228
            :.| |:.|  |:..|...:|.:  |..||..|..:     .:|::...|.|
Yeast   171 SND-ELFRDFLLRAAKTSLGSK--IVSKDHDRFAEMAVEAVINVMDKDRKD-------------- 218

  Fly   229 SKVEFANALVMISLKKITGL-------SQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNK-- 284
              |:|       .|.|:.|.       |:::.|           :|:.:|.|...:...||.|
Yeast   219 --VDF-------DLIKMQGRVGGSISDSKLING-----------VILDKDFSHPQMPKCVLPKEG 263

  Fly   285 ---LRLGLQVCAVKSP--------------------SYGHHR-KELIGDISAATGATI------F 319
               ::|.:..|..:.|                    :|...: ||:|.|:..| ||.:      |
Yeast   264 SDGVKLAILTCPFEPPKPKTKHKLDISSVEEYQKLQTYEQDKFKEMIDDVKKA-GADVVICQWGF 327

  Fly   320 GDDINYSKMEEAKLEDL-------GQVGEAV-ISKDSTMLLQ----GKPKTGLLEMRIQQIQDEL 372
            .|:.|:..::    .||       ||..|.: ||.:..::.:    .|.|.|......:|.....
Yeast   328 DDEANHLLLQ----NDLPAVRWVGGQELEHIAISTNGRIVPRFQDLSKDKLGTCSRIYEQEFGTT 388

  Fly   373 AEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEG-IVPGGG 436
            .::.:..||        |..||.|... :.|.:::.|:|.:..:.|:|...|..:::. :|.|||
Yeast   389 KDRMLIIEQ--------SKETKTVTCF-VRGSNKMIVDEAERALHDSLCVVRNLVKDSRVVYGGG 444

  Fly   437 TAFLRCIPYLQELKTESADLQKGVDI-----VCNALRMPCQTIAQNAGVDGPMVVAKVLNGSE-- 494
            .|.:.    :....:|.||.|:|:|.     ...||.....|:|:|:|:| |:.....|...:
Yeast   445 AAEVT----MSLAVSEEADKQRGIDQYAFRGFAQALDTIPMTLAENSGLD-PIGTLSTLKSKQLK 504

  Fly   495 ----DYGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVITDSRND 547
                :.|.|.:|.....:.|..::||....:..|..|..:..::...:.||...:::
Yeast   505 EKISNIGVDCLGYGSNDMKELFVVDPFIGKKQQILLATQLCRMILKIDNVIISGKDE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	130/571 (23%)
CCT5	NP_012598.1	TCP1_epsilon	23..555	CDD:239455	128/569 (22%)