Protein Alignment Hsp60B and TCM62

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_009600.2
• Gene: TCM62 / 852332
• SGDID: S000000248
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 642
• Identity: 109/642 - (16%)
• Similarity: 233/642 - (36%)
• Gaps: 181/642 - (28%)

  Fly     1 MFRSCVPK-AITSSRCFARMYSKDVRFGSGVRAM--MIRGVDILADAVAVTMGPKGRSVIVERPW 62
            |.|:|:.| ....::|..:.....:.....::.:  .:.|:.:|..  .:|.....:::|.|..:
Yeast     1 MLRNCLRKLGNHQTKCSVKTLHTPIYRTKNLQVLRDTLSGIKLLEK--IITSSSYNKTLIYEPKY 63

  Fly    63 TS-PKITKDGFTVARSIALK--------DQHMN-------------LGAKLVQD-VADNTNESAG 104
            .| |::.....|:.....::        |:..|             :|.:|..| :.||.
Yeast    64 KSKPQVVSSHDTMRLHNVMRELLDSLQVDEATNTRLQSNRPRKLGRVGLQLFMDCIQDNL----- 123

  Fly   105 DGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQQVA--- 166
              |.|:|.|..::.:..|..     ...|:..|:...:..::|.|.:....|:::.::..:.
Yeast   124 --TATSTSLTCSLLEHYFKY-----PEKEVTNGIKAGLRYIRDFLAKNKIIVKSQNDVDALVEQL 181

  Fly   167 TLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQGLRFDNG-------YVSPFFVN 224
            |:|::....|.|::.....::.....:.|.:|.:..||:::.:|.::..|       |:....:.
Yeast   182 TMSSSDSQSIKRVLKAINYELFSDDIVRVINGNKTYDEVDVSKGWKYPAGILDSNEAYLRSLELP 246

  Fly   225 SSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRP-LIIIAEDISGEALNALVLNK---- 284
            :.|...:: .:.||::....:...::|:..:..:.:.|:. |:|:..|.:|:||.::.:|.
Yeast   247 TKKLVSID-KDMLVLMYDGTLRDANKILPTITYARKLRKSVLLIVNGDCTGDALTSVTINNNRNK 310

  Fly   285 --------------------------------LRLGLQVCAVKSPSYGHHRKELIGDISAATGAT 317
                                            |||.....::.||.|    ..|:.....|
Yeast   311 RENNESRIVVLKYSKKANNDLAPQENLDFIKFLRLPCGYDSIYSPEY----SPLVPSKMCA---- 367

  Fly   318 IFGDDINYSKMEEAKLEDLGQVGEAVI--SKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPE 380
                |..|..:|..|    ...|||.:  |.|:..:....||:.|
Yeast   368 ----DKYYGSIESIK----ATTGEAFLYNSIDAEAIPNKVPKSFL-------------------- 404

  Fly   381 QRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRA-AIEEGIVPGGGTAFLRCIP 444
                         :....|.|||.:|:|::.:::.:.:.||.... .:.:|.:||.|.:.|:.||
Yeast   405 -------------QNTVTLSIGGHNEIEIDRRRNAIDNCLNNVLCHGLAKGFIPGYGISLLKAIP 456

  Fly   445 YLQELKTESADL--QKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSEDYGYD-------- 499
            .|.|||....:.  :.|::.|.:|:.:|.:...:||                 |||:
Yeast   457 GLNELKANEPNFMTKVGINAVLSAVILPSEVAFKNA-----------------YGYNYYEINSLI 504

  Fly   500 --------------AMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVIT 542
                          :...|....|:.|.::|...:.:.:........||::...:||
Yeast   505 AGAINEKSFPMAKFSPNSEPVNTVKDGNLEPWSKMDSCLAGVETFIELLTSCNTIIT 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	105/633 (17%)
		GroEL	22..543	CDD:239460	104/620 (17%)
TCM62	NP_009600.2	PTZ00114	124..492	CDD:185455	76/422 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45633
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910