Protein Alignment Hsp60B and CCT6

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_010474.3
• Gene: CCT6 / 851768
• SGDID: S000002596
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 589
• Identity: 139/589 - (23%)
• Similarity: 233/589 - (39%)
• Gaps: 161/589 - (27%)

  Fly    41 LADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESAGD 105
            |...:...:||||...::.....:.|:||||    :.:..:.|..:..|.|:...|...:|..||
Yeast    29 LQSVLETNLGPKGTLKMLVDGAGNIKLTKDG----KVLLTEMQIQSPTAVLIARAAAAQDEITGD 89

  Fly   106 GTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLK-----EMSKA--VETREEIQ 163
            ||||...|...:.::....|..|.:|..|..|..:|   .|:.:|     ::||.  ...||.:.
Yeast    90 GTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIA---RKESMKFLDEFKISKTNLSNDREFLL 151

  Fly   164 QVA--TLSANGDTEIGRLIGE-ATDKVGPRGTITVKDGKRLKDELNI------------------ 207
            |||  :|....|.::..::.. .||.|     ::|.|.:  .|.|::
Yeast   152 QVARSSLLTKVDADLTEVLTPIVTDAV-----LSVYDAQ--ADNLDLHMVEIMQMQHLSPKDTTF 209

  Fly   208 IQGLRFDNG-------------YV---------------SPFFVNSS------KGSKVEFANALV 238
            |:||..|:|             ||               |.||.:|:      ..|:.:|.:|
Yeast   210 IKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASERKFVDA-- 272

  Fly   239 MISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHR 303
              .||||..|...|.|::.   .:..:||..:.|...:|:....:.: |.|:    ::......|
Yeast   273 --KLKKIIDLKNEVCGMDP---DKGFVIINQKGIDPMSLDVFAKHNI-LALR----RAKRRNMER 327

  Fly   304 KELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTGLLEMRIQQI 368
            .:|:      ||    |:..|       .:|||           |..:|   ..:||:      .
Yeast   328 LQLV------TG----GEAQN-------SVEDL-----------SPQIL---GFSGLV------Y 355

  Fly   369 QDELAEKQIK--PEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAI-EEG 430
            |:.:.|::..  .|..|         .|...:| |.|.:...:.:.||.|.|.|.|....: ::.
Yeast   356 QETIGEEKFTYVTENTD---------PKSCTIL-IKGSTHYALAQTKDAVRDGLRAVANVLKDKN 410

  Fly   431 IVPGGGTAFLRCIPYLQELKTESADLQK---------GVDIVCNALRMPCQTIAQNAGVDGPMVV 486
            |:||.|..::....||:     ||::.|         |::....||.:..:|:.:|:|.|...|:
Yeast   411 IIPGAGAFYIALSRYLR-----SANMNKLGAKGKTKTGIEAFAEALLVIPKTLVKNSGFDPLDVL 470

  Fly   487 AKV---LNGSED------YGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVIT 542
            |.|   |:.::|      .|.|....:.|....:||.|..:|||.|||.|.|:||.|...:.::.
Yeast   471 AMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRNAITGATGIASNLLLCDELLR 535

  Fly   543 DSRN 546
            ..|:
Yeast   536 AGRS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	139/589 (24%)
		GroEL	22..543	CDD:239460	138/584 (24%)
CCT6	NP_010474.3	chap_CCT_zeta	2..542	CDD:274088	139/589 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810