Protein Alignment Hsp60B and Bbs10

DIOPT Version :10

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001102756.1
• Gene: Bbs10 / 500832
• RGDID: 1560748
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 104/567 - (18%)
• Similarity: 169/567 - (29%)
• Gaps: 236/567 - (41%)

  Fly    35 IRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKLVQDVADNT 99
            :|..::|.......:||:|..|:..:|.....:::||..:..::.|:..   |...:|..|:.:.
  Rat    11 LRVAEVLETIANRCVGPEGGLVLCTKPTGEVLLSRDGGCLLEALHLEHP---LARMIVACVSSHL 72

  Fly   100 NESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAVETREEIQ- 163
            .:: |||..|..:..                 ..:.||:....:..||..        |.|:||
  Rat    73 KKT-GDGAKTFIIFL-----------------CHLLRGLHAIGEKEKDSF--------TSEDIQS 111

  Fly   164 ---------------------QVATL------------------SANGDT--------------- 174
                                 |..||                  ||.|.|
  Rat   112 HERHWKNCCQWKSISRALLRFQTQTLGCIVDQHLSRHYLSAFSSSAEGRTLCRRSLELLLEPYFC 176

  Fly   175 -------------------------EIGRLIGEATD------KVGPRGTITVKDGKRLKDELNII 208
                                     |.|..:.|..|      .||..| :.|.:.:       |:
  Rat   177 GRVGRNNHRFISQLMCDYVFKCMACESGIEVFEFLDNCFVELNVGVTG-LPVSESR-------IV 233

  Fly   209 QGLRF----------DNG--------YVSPFFVNSSK----GSKVEF--ANALVMISLKKITG-- 247
            .||..          |.|        .:.|.|.:||.    .|:.:|  :.:.:|...|.:..
  Rat   234 DGLVLPRDFSVYCPADGGIRMVIVTEILQPLFSSSSSEFVLDSETQFQASQSWIMDRTKTVMNHL 298

  Fly   248 LSQIVKGLEQSLRQ--------RRPLIIIAEDISGEALNALVLNKLRLGLQVCA----------- 293
            .|..||.|..|::|        |...|.:.|.:|.|.::   |.:...||..|.
  Rat   299 RSHNVKLLLSSVKQPDLVTYCARLNSISVVECLSSEEVS---LVQRITGLSPCVLPELASQCHIA 360

  Fly   294 ------------VKSPSYGH-----------HRKELIGDI--------SAATGA-----TIFGD- 321
                        |:|..|.|           |...|.|.:        ||..||     .:|.|
  Rat   361 DSALVRFCKPLIVRSGRYAHLGLVSTCAFVPHCVVLCGPVLGLVQQHESAFHGAFKMLRQLFTDL 425

  Fly   322 DINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLR 386
            |:|      ..::...:...:.::..|.......||||       :.||.:|:.:.|.|.:.||.
  Rat   426 DLN------CMIQTKERRNPSPLADSSNRESSHSPKTG-------KYQDVVAKNKDKLETQTRLE 477

  Fly   387 --QRLSALTKGVAVLHIGGGSE------VEVNE-------KKDRVVD 418
              .||.|....:....:....:      .:.||       :|.|:||
  Rat   478 VYPRLGASDTELITCKLWSAHKETSIDPSQTNEIPKRLSPEKSRIVD 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	104/567 (18%)
Bbs10	NP_001102756.1	Cpn60_TCP1	13..>424	CDD:395068	79/450 (18%)