Protein Alignment Hsp60B and cct5

DIOPT Version :10

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_997778.1
• Gene: cct5 / 322258
• ZFINID: ZDB-GENE-030131-977
• Length: 541
• Species: Danio rerio
• Alignment Length: 570
• Identity: 116/570 - (20%)
• Similarity: 222/570 - (38%)
• Gaps: 113/570 - (19%)

  Fly    28 SGVRAMM--IRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAK 90
            :|:.|:.  |.....:|:.:..::||.|...::........:|.||.|:   :::.|....: ||
Zfish    29 TGLEALKSHILAAKAVANTLRTSLGPNGLDKMMVDKDGEVTVTNDGATI---LSMMDVDHQI-AK 89

  Fly    91 LVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKA 155
            |:.:::.:.::..|||||...|||.|:.::....:..|.:|:.|..|...|..:..::|.::..:
Zfish    90 LMVELSKSQDDEIGDGTTGVVVLAGALLEQAEQLLDRGIHPIRIADGYDQAAKIAIEQLDKIGDS 154

  Fly   156 V----ETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKD-----------------GK 199
            .    ...|.:.|.| ::..|...|.|...:..: :.....:||.|                 |.
Zfish   155 FPVDPNNTESLVQTA-MTTLGSKVINRCHRQMAE-IAVNAILTVADMERKDVDFELIKVEGKVGG 217

  Fly   200 RLKDELNIIQGLRFDNGYVSPFFVNSSKGSKV------------EFANALVMISLKKITGLSQIV 252
            :|:| ..:|:|:..|..:..|......|.:|:            :..:.|.:.|::....|.:..
Zfish   218 KLED-TQLIKGVIVDKEFSHPQMPKVLKDTKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYE 281

  Fly   253 KG-LEQSLRQRRP----LIIIAEDISGEALNALVLNKLRLGLQVCAVKSPS---YGHHRKELIGD 309
            |. .::.:||.:.    |.|.......||.:.|:.|:|           |:   .|....||
Zfish   282 KDKFQEMIRQVKENGANLAICQWGFDDEANHLLLQNEL-----------PAIRWVGGPEIEL--- 332

  Fly   310 ISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVI--SKDSTMLLQGKPKTGLLEMRIQQIQDEL 372
            |:.|||..|..   .:.::...||...|.|.|...  :||..::             |::.::..
Zfish   333 IAIATGGRIVP---RFCELTPEKLGTAGLVKEICFGTTKDRMLV-------------IEECKNSR 381

  Fly   373 AEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEG-IVPGGG 436
            |                       ..:.|.||:::.:.|.|..:.|||...|..:.:. ||.|||
Zfish   382 A-----------------------VTIFIRGGNKMIIEEAKRALHDALCVIRNLVRDNRIVYGGG 423

  Fly   437 TAFLRCIPYLQELKTESADL-QKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSEDYGYDA 500
            .:.:.|...:.|...:...| |..:....:||.:....:|:|:|::....:.:|..........|
Zfish   424 ASEIACALAVNEAADKCPSLEQYAMRAFADALEVIPMALAENSGLNPIQTMTEVRARQVKENNSA 488

  Fly   501 MGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLS-TTEVVITDSRNDDL 549
            :|.: |..:....:....|:.|.|    |....:| .|:||....:.||:
Zfish   489 LGID-CLHLSTNDMKQQHVIETLI----GKKQQISLATQVVKMILKIDDI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	114/562 (20%)
cct5	NP_997778.1	TCP1_epsilon	10..535	CDD:239455	116/570 (20%)