Protein Alignment Hsp60B and Tcp1

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_038714.2
• Gene: Tcp1 / 21454
• MGIID: 98535
• Length: 556
• Species: Mus musculus
• Alignment Length: 622
• Identity: 132/622 - (21%)
• Similarity: 231/622 - (37%)
• Gaps: 165/622 - (26%)

  Fly    27 GSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKL 91
            |..||:..:.....:|:.|..:.||.|...::........||.||.|:.:  .|:.:|.  .||:
Mouse    14 GEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILK--LLEVEHP--AAKV 74

  Fly    92 VQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAV 156
            :.::||..::..|||||:..::|..:.|.....:....:|..:..|..||
Mouse    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLA--------------- 124

  Fly   157 ETREEIQQV-ATLSANGDTEIGR--LIGEATDKVGPRGTITVKDGKRLKDELNIIQGLRFDNGYV 218
             .:|.::.: ..|..|.| |:||  ||..|...:..: .|.:.........::.:..:::.:...
Mouse   125 -CKEAVRYINENLIINTD-ELGRDCLINAAKTSMSSK-IIGINGDYFANMVVDAVLAVKYTDARG 186

  Fly   219 SPFF-VNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEALNALV- 281
            .|.: |||              :::.|..|.|||...|                |:|.|||.:|
Mouse   187 QPRYPVNS--------------VNILKAHGRSQIESML----------------INGYALNCVVG 221

  Fly   282 ---------------------LNKLRLGLQVCAVKSPSYGHHRKELIGDIS-------AATGATI 318
                                 ..|::||:|| .:..|......::...||:       .||||.:
Mouse   222 SQGMPKRIVNAKIACLDFSLQKTKMKLGVQV-VITDPEKLDQIRQRESDITKERIQKILATGANV 285

  Fly   319 F----GDDINYSK---------MEEAKLEDLGQV----GEAVISKDSTMLLQGKP--KTGLLEMR 364
            .    |.|..|.|         :......||..|    |.:::|  :...|:|:.  :..:|...
Mouse   286 ILTTGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGASILS--TLANLEGEETFEVTMLGQA 348

  Fly   365 IQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIE- 428
            .:.:|:.:.:.::...:..:.|...|.:.:        |.::...:|.:..:.|||...:..:|
Mouse   349 EEVVQERICDDELILIKNTKARTSASIILR--------GANDFMCDEMERSLHDALCVVKRVLEL 405

  Fly   429 EGIVPGGGTAFLRCIPYLQELKTES--------ADLQKGVDIVCNALRMPCQTIAQNAGVDGPMV 485
            :.:|||||........||:...|..        |:..:.:.::.|       |:|.||..|...:
Mouse   406 KSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPN-------TLAVNAAQDSTDL 463

  Fly   486 VAKV--------LNGSED----YGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTE 538
            |||:        :|....    .|.|.:..:.....:.|:.:||.|         .|.||...||
Mouse   464 VAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIV---------KVKSLKFATE 519

  Fly   539 VVITDSRNDDLL-----SKLSGAG--------GGMDD 562
            ..||..|.|||:     ||....|        |.:||
Mouse   520 AAITILRIDDLIKLHPESKDDKHGSYENAVHSGALDD 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	129/616 (21%)
		GroEL	22..543	CDD:239460	121/588 (21%)
Tcp1	NP_038714.2	chap_CCT_alpha	5..540	CDD:274081	128/604 (21%)
		TCP1_alpha	9..535	CDD:239451	126/599 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900