Protein Alignment Hsp60B and hsp-60

DIOPT Version :10

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_497429.1
• Gene: hsp-60 / 175316
• WormBaseID: WBGene00002025
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 327/580 - (56%)
• Similarity: 417/580 - (71%)
• Gaps: 28/580 - (4%)

  Fly    18 RMYSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKD 82
            |.|:|||:||:..|..|:.||::|||||:||||||||:||:|:.|.||||||||.|||:||.|||
 Worm    15 RSYAKDVKFGAEGRQAMLVGVNLLADAVSVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIDLKD 79

  Fly    83 QHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKD 147
            ::.||||||:||||:..||.||||||.|||||||||||||..|..|.|.||||||||.||:||..
 Worm    80 KYQNLGAKLIQDVANKANEEAGDGTTCATVLARAIAKEGFESIRQGGNAVEIRRGVMNAVEVVVA 144

  Fly   148 KLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDELNIIQGLR 212
            :||::||.|.|.|||.||||:||||||.:|.||.:|..|||..|.|||||||.|.|||.:|:|::
 Worm   145 ELKKISKKVTTPEEIAQVATISANGDTVVGNLISDAMKKVGTTGVITVKDGKTLNDELELIEGMK 209

  Fly   213 FDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAEDISGEAL 277
            ||.||:||:|:.|:||:|||:..|||::|.|||:.:..||..||.:.:.||||:|||||:.||||
 Worm   210 FDRGYISPYFITSAKGAKVEYEKALVLLSEKKISQVQDIVPALELANKLRRPLVIIAEDVDGEAL 274

  Fly   278 NALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLEDLGQVGEA 342
            ..||||:|::||||.|:|:|.:|.:||..:.|:..||||||||||.|..|:|:....|||:|.|.
 Worm   275 TTLVLNRLKVGLQVVAIKAPGFGDNRKNTLKDMGIATGATIFGDDSNLIKIEDITANDLGEVDEV 339

  Fly   343 VISKDSTMLLQGKPKTGLLEMRIQQIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEV 407
            .|:||.|:||:|:.....:|.||:.|.||: |:.....::::|.:||:.|:||||||.|||||||
 Worm   340 TITKDDTLLLRGRGDQTEIEKRIEHITDEI-EQSTSDYEKEKLNERLAKLSKGVAVLKIGGGSEV 403

  Fly   408 EVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQELKTESADLQKGVDIVCNALRMPCQ 472
            ||.||||||.|||.|||||:|||||||||.|.||.:..|:..|..:.|.|.||:||..||..|..
 Worm   404 EVGEKKDRVTDALCATRAAVEEGIVPGGGVALLRSLTALKNYKAANEDQQIGVNIVKKALTQPIA 468

  Fly   473 TIAQNAGVDGPMVVAKVL-NGSEDYGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLST 536
            ||.:|||::...::.:|. |.:..|||||:..::..:.|.||||||||:|||:.||:||||||:|
 Worm   469 TIVKNAGLEPSSIIDEVTGNSNTSYGYDALNGKFVDMFEAGIIDPTKVVRTALQDASGVASLLAT 533

  Fly   537 TEVVITDSRNDDLLSKLSGAGGGMDDGLDMNMGGLEELAALSGLGGMGGMGGMGGMGGMG 596
            ||.|:|:      :.|....||                    ..||||||||||||||||
 Worm   534 TECVVTE------IPKEEAVGG--------------------PAGGMGGMGGMGGMGGMG 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	305/521 (59%)
hsp-60	NP_497429.1	GroEL	19..540	CDD:239460	305/521 (59%)