Protein Alignment Hsp60B and cct-2

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_741031.1
• Gene: cct-2 / 174421
• WormBaseID: WBGene00000378
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 133/586 - (22%)
• Similarity: 237/586 - (40%)
• Gaps: 148/586 - (25%)

  Fly    27 GSGVRAMMIRGVDILADAVAVTMGPKG--RSVIVERPWTSP--KITKDGFTVARSIALKDQHMNL 87
            |...|.....|...:.|.|..|:||||  :.:|...|.::.  |:|.||.|:.:||.:.    |.
 Worm    16 GESARLSSFVGAIAIGDLVKSTLGPKGMDKILISGNPESAGGIKVTNDGATILKSIGVD----NP 76

  Fly    88 GAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEM 152
            .||::.|::...:...|||||:.||||..:.||....:....:|..|..|...|:.:.::.||:.
 Worm    77 AAKVLVDMSMTQDHEVGDGTTSVTVLAAELLKEAEKLVNQRIHPQTIISGYRRALGIAQESLKKS 141

  Fly   153 SKAVET----REEIQQVATLSANGDTEIG-RLIGE--------ATDKVGPRGTITVKDGKRLKDE 204
            |  :|:    |:::.::|.      |.:| :::.:        |.|.|     :.:|....| |.
 Worm   142 S--IESGDNIRDDLLKIAR------TTLGSKILSQHKEHFAQLAVDAV-----LRLKGSGNL-DA 192

  Fly   205 LNIIQGL-------RFDNGYVSPFFVNSSKGSKVEFANAL------------VMISLKKITGLSQ 250
            :.||:.|       ..|.|::........:..:||.|..|            |..|..::.|:::
 Worm   193 IQIIKKLGGSMNESYLDEGFLLEKLPGMFQPRRVEKAKILIANTPMDTDKVKVFGSRVRVDGVAK 257

  Fly   251 IVKGLE--QSLRQRRPL-IIIAEDISGEALNALVLN---KLRLGLQVCAVKSPSY-GHHRKELI- 307
            :.: ||  :.|:.:..: .|:|.:.:......|:.|   :|....:|.|::...: |..|..|:
 Worm   258 VAE-LEAAEKLKMKEKVDKILAHNCNVFINRQLIYNYPEQLFADAKVMAIEHADFEGIERLALVL 321

  Fly   308 -GDISAATGATIFGDDINYSKMEEAKLEDLGQVGEAVISKDSTMLLQGKPKTG-----LLEMRIQ 366
             |:|.:           .:...:.|:......:.|.:|.:|..:...| .|.|     :|....|
 Worm   322 GGEIVS-----------TFDSPQTAQFGSCDLIEEIMIGEDRLLRFSG-VKLGEACSVVLRGATQ 374

  Fly   367 QIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHI--------GGGSEVEVNEKKDRVVDALNAT 423
            ||.|| :|:.:    .|.|         .|.|.|:        .|.||:.::.     ..|:.|.
 Worm   375 QILDE-SERSL----HDAL---------CVLVTHVKESKTVAGAGASEILMSS-----AIAVEAQ 420

  Fly   424 RAAIEEGIVPGGGTAFLRCIPYLQELKTESADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAK 488
            :.|.:|.:..   .||.|.   |.:|.|          |:|:           |||:|...:|.:
 Worm   421 KVAGKEALAV---EAFGRA---LAQLPT----------IICD-----------NAGLDSAELVTR 458

  Fly   489 V----LNGSEDYGYDAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVITDSRNDDL 549
            :    .||..:.|.|....|...:.:.|:|:...|....::.||      ..||.::   |.||:
 Worm   459 LRAEHANGRHNMGIDIEKGEVADVTKLGVIESYNVKLCMVSSAA------EATEQIL---RVDDI 514

  Fly   550 L 550
            :
 Worm   515 I 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	133/586 (23%)
		GroEL	22..543	CDD:239460	130/577 (23%)
cct-2	NP_741031.1	chap_CCT_beta	5..522	CDD:274082	133/586 (23%)
		TCP1_beta	6..520	CDD:239452	133/586 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810