Protein Alignment Hsp60B and cct-1

DIOPT Version :9

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_495722.1
• Gene: cct-1 / 174318
• WormBaseID: WBGene00000377
• Length: 549
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 138/610 - (22%)
• Similarity: 242/610 - (39%)
• Gaps: 155/610 - (25%)

  Fly    27 GSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVARSIALKDQHMNLGAKL 91
            |.|:|:..:.....:|:.|..::||.|...::........:|.||.|:.:.:.::    :...|:
 Worm    18 GQGIRSQNVTAAVAIANIVKSSLGPVGLDKMLVDDVGDVIVTNDGATILKQLEVE----HPAGKV 78

  Fly    92 VQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLKEMSKAV 156
            :.::|...:|..|||||:..::|..:.|.....:....:|..|..|..||   .|:.:|.:|:.:
 Worm    79 LVELAQLQDEEVGDGTTSVVIVAAELLKRADELVKQKVHPTTIINGYRLA---CKEAVKYISENI 140

  Fly   157 E-TREEIQQVATLSANGDTEIGRLIGEATD-------------KVGPRGTITV---------KDG 198
            . |.:.|.:.:.::|...:...::||...|             :|...|.:|.         ..|
 Worm   141 SFTSDSIGRQSVVNAAKTSMSSKIIGPDADFFGELVVDAAEAVRVENNGKVTYPINAVNVLKAHG 205

  Fly   199 KRLKDELNIIQGLRFDNGYVS---PFFVNSSKGSKVEFANALVMISLKKITGLSQIVKG---LEQ 257
            |..::.: :::|...:....|   |..|.::|.:.::|:    ::..|...|:|.:|:.   ||.
 Worm   206 KSARESV-LVKGYALNCTVASQAMPLRVQNAKIACLDFS----LMKAKMHLGISVVVEDPAKLEA 265

  Fly   258 SLRQRRPLIIIAEDISGEALNALVLNKLRLGLQV----------CA---VKSPSYGHHR--KELI 307
            ..|:.       .||:...::.:    |:.|..|          |.   |:|.:....|  |..:
 Worm   266 IRREE-------FDITKRRIDKI----LKAGANVVLTTGGIDDLCLKQFVESGAMAVRRCKKSDL 319

  Fly   308 GDISAATGATIFGDDINYSKMEEAKLED---LGQVGEAV---ISKDSTMLLQGKPKTGLLEMRIQ 366
            ..|:.|||||:   .::.:.:|..:..|   ||...|.|   ||.|..:|::|
 Worm   320 KRIAKATGATL---TVSLATLEGDEAFDASLLGHADEIVQERISDDELILIKG------------ 369

  Fly   367 QIQDELAEKQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIE-EG 430
                        |:.|          |....:|.  |.::|.::|.:..|.|:|...|..:| :.
 Worm   370 ------------PKSR----------TASSIILR--GANDVMLDEMERSVHDSLCVVRRVLESKK 410

  Fly   431 IVPGGG------TAFLRCIPYLQELKTESADLQKGVDIVCNALRMPCQTIAQNAGVDGPMVVAKV 489
            :|.|||      :.||.  .|.|.|.:..   |..|....:||.:..:.:|.||..|...:|.|:
 Worm   411 LVAGGGAVETSLSLFLE--TYAQTLSSRE---QLAVAEFASALLIIPKVLASNAARDSTDLVTKL 470

  Fly   490 ------------LNGSEDYGYDAMGDEYCRLVEKGIIDPTK---VLRTAITDAAGVASLLSTTEV 539
                        |...:..|.|         :|:|.|...|   :|..|::.   |.||...||.
 Worm   471 RAYHSKAQLIPQLQHLKWAGLD---------LEEGTIRDNKEAGILEPALSK---VKSLKFATEA 523

  Fly   540 VITDSRNDDL--LSKLSGAGGGMDD 562
            .||..|.|||  |.|....||  ||
 Worm   524 AITILRIDDLIKLDKQEPLGG--DD 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	134/604 (22%)
		GroEL	22..543	CDD:239460	127/587 (22%)
cct-1	NP_495722.1	chap_CCT_alpha	9..543	CDD:274081	134/603 (22%)
		TCP1_alpha	13..538	CDD:239451	133/598 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810