Protein Alignment Hsp60B and CCT2

DIOPT Version :10

• Sequence 1: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_318752.5
• Gene: CCT2 / 1279082
• VectorBaseID: AGAMI1_012123
• Length: 534
• Species: Anopheles gambiae
• Alignment Length: 563
• Identity: 126/563 - (22%)
• Similarity: 219/563 - (38%)
• Gaps: 109/563 - (19%)

  Fly    27 GSGVRAMMIRGVDILADAVAVTMGPKGRSVIV---ERPWTSPKITKDGFTVARSIALKDQHMNLG 88
            |...|.....|...:.:.|..|:||||...|:   .|.....::|.||.|:.|::.:.    |..
Mosquito    19 GEIARLSSFVGAIAIGELVKSTLGPKGMDKILVANGRNAGQIEVTNDGATILRAVGVD----NPA 79

  Fly    89 AKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVEIRRGVMLAVDVVKDKLK--- 150
            ||::.|::...::..|||||:.||.|..:.:|....:....:|..|..|...|.||.:..|:
Mosquito    80 AKILVDMSRVQDDEVGDGTTSVTVFAAELIREAEKLVEQKLHPQTIIAGWRQAADVARTALQGAA 144

  Fly   151 --EMSKAVETREEIQQVA--TLS----ANGDTEIGRLIGEATDKVGPRGTITVKDGKRLK----- 202
              ..:.....||::..:|  |||    :.......:|..:|..::...|:::..  :|:|
Mosquito   145 ADNSANQERFREDLLNIARTTLSSKILSQHKEHFAKLAVDAVLRLKGSGSLSAI--QRIKKLGGC 207

  Fly   203 -DELNIIQGLRFDN--GYVSPFFVNSSKGSKVEFANA-------LVMISLKKITGLSQI--VKGL 255
             :|..:.:|...|.  |...|   .|.|.:.:..||.       .|..|..|:..:|:|  ::..
Mosquito   208 LEESFLDEGFLLDKKPGVHQP---KSVKNANILIANTPMDTDKIKVFGSSIKVDSMSKIAELEVA 269

  Fly   256 EQSLRQRRPLIIIAEDISGEALNALVLN---KLRLGLQVCAVKSPSY-GHHRKELIGDISAATGA 316
            |:...:.:...|:|.:|:......|:.|   :|.....|.|::...: |..|..|:      ||.
Mosquito   270 EKEKMKEKVDKILAHNINVFINRQLIYNYPEQLFADAGVMAIEHADFDGIERLALV------TGG 328

  Fly   317 TIFGDDINYSKMEEAKLEDLGQ---VGEAVISKDSTMLLQGKPK----TGLLEMRIQQIQDELAE 374
            .|      .|..:...|..||:   :.:.:|.:|:.:...|.|.    |.::....|||.|| ||
Mosquito   329 EI------VSTFDNPDLVKLGKCDLIEQVMIGEDTLLRFSGVPLGEACTVVIRGATQQIIDE-AE 386

  Fly   375 KQIKPEQRDRLRQRLSALTKGVAVLHIGGGSEVEVNEKKDRVVDALNATRAAIEEG-IVPGGGTA 438
            :.                      ||                 |||....|.::|. :|.|||.:
Mosquito   387 RS----------------------LH-----------------DALCVLAATVKESRVVYGGGCS 412

  Fly   439 FLRCIPYLQELKTESADLQ-KGVDIVCNALRMPCQTIAQNAGVDGPMVVAKV----LNGSEDYGY 498
            .......:.:|..|:|..: ..::....||......||.|||.|...:|:::    ..|....|.
Mosquito   413 ETLMATAVFKLAAETAGKEAMAIESFGRALMQLPTIIADNAGYDSAQLVSELRAGHSQGKSTMGL 477

  Fly   499 DAMGDEYCRLVEKGIIDPTKVLRTAITDAAGVASLLSTTEVVI 541
            |....:...:.|.||.:...|.|..:..||..|.::...:.::
Mosquito   478 DMNNGKVGCMKELGITESFAVKRQVLMSAAEAAEMILRVDNIL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	126/563 (22%)
CCT2	XP_318752.5	None