Protein Alignment heph and PTB2

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_200130.1
• Gene: PTB2 / 835399
• AraportID: AT5G53180
• Length: 429
• Species: Arabidopsis thaliana
• Alignment Length: 519
• Identity: 141/519 - (27%)
• Similarity: 199/519 - (38%)
• Gaps: 186/519 - (35%)

  Fly   367 SKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKG--KNQAFIEMADEISATSMVSCYTVT--P 427
            |||:||||:|.|..|.::|.||.|||.|.|.....|  :||||||..|...|..|:|.|..:  |
plant    17 SKVLHLRNLPWECTEEELIELGKPFGTVVNTKCNVGANRNQAFIEFEDLNQAIQMISYYASSSEP 81

  Fly   428 PQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNS 492
            .|:||:.||:|:||.:|
plant    82 AQVRGKTVYLQYSNRQE------------------------------------------------ 98

  Fly   493 AMGILQNTSAVNAGGNTNAAGGPNTVLRVIVE---SLMYPVSLDILHQIFQRYGKVLKIVTFTKN 554
               |:.|.:..:..||         ||.|.:|   :.|  ||:|:||.:|..:|.|.||.||.|.
plant    99 ---IVNNKTTADVVGN---------VLLVTIEGDDARM--VSIDVLHLVFSAFGFVHKITTFEKT 149

  Fly   555 NSFQALIQYPDANSAQHAKSLLDGQNIYN-------GCCTLRIDNSKLTALNVKYNNDKSRDFTN 612
            ..:|||:|:.||.:|..||..|||::|..       |.|:|:|..|..|.|.||:.:.:|||:||
plant   150 AGYQALVQFTDAETATAAKLALDGRSIPRYLLAETVGQCSLKITYSAHTDLTVKFQSHRSRDYTN 214

  Fly   613 PALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNA 677
            |.||       :.|:|                   :...|..|.||
plant   215 PYLP-------VAPSA-------------------IDSTGQVAVGV------------------- 234

  Fly   678 LPNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLN-EEMVTPDALFTLFGVYGDVQRVKILYNKK 741
                             ....|...|||||.|..| :..||.|.|..:|..:|:||:: .:::|.
plant   235 -----------------DGKKMEPESNVLLASIENMQYAVTLDVLHMVFAAFGEVQKI-AMFDKN 281

  Fly   742 D--SALIQMAEPQQAYLAMSHL-----------------------------DKLRLWGKPIRVMA 775
            .  .||||.::.|.|.:|...|                             |:.|.:..|...:.
plant   282 GGVQALIQYSDVQTAVVAKEALEGHCIYDGGFCKLHITYSRHTDLSIKVNNDRSRDYTMPNPPVP 346

  Fly   776 SKHQAVQLPKEGQPD-----AGLTRDYSQNPLHRFKKPGSK----------NYQNIYPPSATLH 824
            ...|.||.|..|.|.     .|......|.|...:.:||.:          |:....|.|:::|
plant   347 MPQQPVQNPYAGNPQQYHAAGGSHHQQQQQPQGGWVQPGGQGSMGMGGGGHNHYMAPPSSSSMH 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	141/519 (27%)
PTB2	NP_200130.1	RRM1_PTBPH1_PTBPH2	16..96	CDD:410087	38/78 (49%)
		RRM2_PTBPH1_PTBPH2	110..204	CDD:241135	41/104 (39%)
		RRM3_PTBPH1_PTBPH2	243..339	CDD:410091	26/96 (27%)