Protein Alignment heph and Ptbp3

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_006238268.3
• Gene: Ptbp3 / 83515
• RGDID: 621671
• Length: 554
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 305/602 - (50%)
• Similarity: 381/602 - (63%)
• Gaps: 88/602 - (14%)

  Fly   323 RGSDELLSQAAVMAPASDNNNQDLA-------TKKAKLE--PGTVLAGGIAKASKVIHLRNIPNE 378
            |||||||....:..|::.||:....       .||.|.:  |        ...|:|:|||.||.:
  Rat    15 RGSDELLPSGVINGPSTMNNSTSAGVYANGNDNKKFKGDRPP--------CSPSRVLHLRKIPCD 71

  Fly   379 SGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHR 443
            ..||:||:||:|||:|||:|:||||:|||:|||.|.:|.:|::.||...|.:|.:.||:|:||||
  Rat    72 VTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHR 136

  Fly   444 ELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAG-- 506
            |||||.                     ||..|.|.|.                ||..|||.:|
  Rat   137 ELKTDN---------------------LPNQARAQAA----------------LQAVSAVQSGNL 164

  Fly   507 ---GNTNAAG----GPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYP 564
               |.|:..|    |.:.|||:|:|:|.|||:|::|||||.::|.||||:||||||.||||:||.
  Rat   165 SLPGATSNEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYA 229

  Fly   565 DANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPT-- 627
            |..:||:||..||||||||.|||||||.||||:||||||||||||||...||.|:....:.|.
  Rat   230 DPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMA 294

  Fly   628 ----AGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLAN 688
                |.|:|::           |.....|. ||.:..|.|.||......|   ||..|...|.|.
  Rat   295 AAFGAPGIMSS-----------PYAGAAGF-APAIAFPQAAGLSVSAVPG---ALGPLTLTSSAV 344

  Fly   689 SGALQTTAPAMRGY--SNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEP 751
            ||.:  ..|...|.  ::||||:|||.:.:||..||.||||||||.||||::|||::||:|||:.
  Rat   345 SGRM--AIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADA 407

  Fly   752 QQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNI 816
            .||.:||:||...||:||.:|...|||||||||:|||.|.|||:|:|.:||||||||||||:|||
  Rat   408 SQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNI 472

  Fly   817 YPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNH 881
            :||||||||||||.|.:.||:|..||.....|||||||.|||||||:||.|||||:.|||::|||
  Rat   473 FPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNH 537

  Fly   882 QLSESNHLRVSFSKSNI 898
            .|.|::|||||||||.|
  Rat   538 DLGENHHLRVSFSKSTI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	290/548 (53%)
Ptbp3	XP_006238268.3	None