Protein Alignment heph and ptbp3

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_009303446.1
• Gene: ptbp3 / 798982
• ZFINID: ZDB-GENE-091116-1
• Length: 522
• Species: Danio rerio
• Alignment Length: 573
• Identity: 296/573 - (51%)
• Similarity: 366/573 - (63%)
• Gaps: 67/573 - (11%)

  Fly   337 PASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLK 401
            |::..|..|....|....|        ...|:|:|:|.:|.|..||:|::||:|||:|||:|:||
Zfish     6 PSTTANGTDSKQYKGDRSP--------CAPSRVLHVRKVPIEVSEAEVVSLGVPFGKVTNLLMLK 62

  Fly   402 GKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPA 466
            ||||||||||.|.:|.:||:.||...|.:|.:.||:|:|||||||||.
Zfish    63 GKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSNHRELKTDN----------------- 110

  Fly   467 SGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVS 531
                ||....|.|.....|:....|.:   |..|:..:.||   ...|.:.|||:|||:|.||||
Zfish   111 ----LPNQGRAQAALQAVNAVHTGNMS---LSGTATASDGG---MMPGQSPVLRIIVENLYYPVS 165

  Fly   532 LDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLT 596
            |::|||||.::|.||||:||||||.||||:||.|..:|.|||..||||||||||||||::.||||
Zfish   166 LEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLT 230

  Fly   597 ALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPP 661
            :||||||||||||||...||.|    |..||....|.|                 ..||||::..
Zfish   231 SLNVKYNNDKSRDFTRLDLPSG----DGQPTLDPTMQT-----------------AFGAPGIISS 274

  Fly   662 -------FALGLGTPLTGGYNNALPN----LAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEM 715
                   ||..:|.|..|....|:|.    |...|.|.:|.:...........:||||||||.:.
Zfish   275 PYPGAAGFAPAIGFPQAGLSMQAMPGALGPLTIPSSAMTGRMAIHGMTPTAIHSVLLVSNLNPDS 339

  Fly   716 VTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQA 780
            ::|..||.||||||||.|||||:|||::||||||:..||.||||||:..||:||.|||..||||.
Zfish   340 ISPHELFILFGVYGDVHRVKILFNKKENALIQMADATQAQLAMSHLNGQRLYGKVIRVTISKHQT 404

  Fly   781 VQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNS 845
            ||||:|||.|.|||:|:|.:||||||||||||:|||:||||||||||||.|.::|.:|:.|.|:.
Zfish   405 VQLPREGQEDQGLTKDFSGSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSTTDDFLKDLFASSG 469

  Fly   846 FEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI 898
            :.|||||||.|||||||:||.|||||:.|||.:|||.|.|::|||||||||.|
Zfish   470 YTVKAFKFFQKDRKMALIQLGSVEEAIQALIHLHNHDLGENHHLRVSFSKSTI 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	290/542 (54%)
ptbp3	XP_009303446.1	hnRNP-L_PTB	27..522	CDD:273733	290/542 (54%)