Protein Alignment heph and ptbp2

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001072479.1
• Gene: ptbp2 / 779934
• XenbaseID: XB-GENE-491012
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 300/587 - (51%)
• Similarity: 387/587 - (65%)
• Gaps: 80/587 - (13%)

  Fly   323 RGSDELLSQAAVMAPASD--------NNNQDLATK-KAKLEPGTVLAGGIAKASKVIHLRNIPNE 378
            ||||||||.:.:..|:|:        |.|.:...| ..|:|         |..|:|:|:|.:|.|
 Frog    14 RGSDELLSGSVLNGPSSNMSSVVVTANGNDNKKFKGDDKME---------AAPSRVLHIRKLPGE 69

  Fly   379 SGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHR 443
            ..|.:|||||:|||:|||:|:||||||||:|:|.|.:|::||:.||...|.:|.:.:|:|:|||:
 Frog    70 VTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAASTMVNYYTTITPHLRNQPIYIQYSNHK 134

  Fly   444 ELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGN 508
            |||||...|.             ....:..:..|..|||::.:|:.:|      :||
 Frog   135 ELKTDSALNQ-------------RAQAVLQAVTAVQTSNSSVTSTAAN------ENT-------- 172

  Fly   509 TNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAK 573
            .::|..|  |||:|::::.|||:||:|||||.::|.||||:||||||.||||:||.|..:||.||
 Frog   173 VSSAQSP--VLRIIIDNMYYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYGDPVNAQQAK 235

  Fly   574 SLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALP--PGEPGVDIMPTAGGLMNTND 636
            ..||||||||.|||||||.|||..||||||||||||:|.|.||  .|:|.:|  |.
 Frog   236 LALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALD--PA--------- 289

  Fly   637 LLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRG 701
               |||......|:  |..||.|.|    ||          :||.||.:.|.:.:.........|
 Frog   290 ---IAAAFAKETSL--LAVPGALSP----LG----------IPNAAAAAAAAAASRVGMHGVSTG 335

  Fly   702 YSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRL 766
            .:.||||||||||||:|.:|||||||||||||||||||||||||||||:..|:.||||||:..::
 Frog   336 GNTVLLVSNLNEEMVSPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMSHLNGQKM 400

  Fly   767 WGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSS 831
            :||.|||..||||.||||:||..|.|||:|:|.:||||||||||||:|||:||||||||||||.:
 Frog   401 YGKIIRVTLSKHQTVQLPREGLDDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPQN 465

  Fly   832 CSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKS 896
            .:|||::..||:....||||||| :|.||||||:.:||||:.|||.:||:.:.:::|||||||||
 Frog   466 ITEDDLRTLFTNTGGNVKAFKFF-QDHKMALLQMSTVEEAIQALIDLHNYNIGDNHHLRVSFSKS 529

  Fly   897 NI 898
            .|
 Frog   530 TI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	283/533 (53%)
ptbp2	NP_001072479.1	hnRNP-L_PTB	57..531	CDD:273733	283/533 (53%)