Protein Alignment heph and hnrnpl2

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001410665.1
• Gene: hnrnpl2 / 573096
• ZFINID: ZDB-GENE-040426-2707
• Length: 522
• Species: Danio rerio
• Alignment Length: 604
• Identity: 157/604 - (25%)
• Similarity: 249/604 - (41%)
• Gaps: 158/604 - (26%)

  Fly   347 ATKKAKLEPGTVLAGGIAK----------ASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLK 401
            |||:.|.|.    .||:|.          .|.|:|:|.:.:...|:|::.....||.::.|:::.
Zfish    15 ATKRQKTEN----EGGMATEGYTDPHKTLPSLVVHVRGLVDGVLESDIVEALQEFGTISYVVLMP 75

  Fly   402 GKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPA 466
            .|.||.:|..|                 |.|....|.::|..::.. .||   .|..:||
Zfish    76 KKRQALVEYED-----------------MNGSCNAVTYANDNQIYI-AGH---PAFVNYS----- 114

  Fly   467 SGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVS 531
                         ||...:...|.:.|..:                   |.||.:.:.:.:||::
Zfish   115 -------------TSQKISRPGDPDDARSV-------------------NNVLLLTIMNPIYPIT 147

  Fly   532 LDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLT 596
            .|:|:.|....|.|.:||.|.| |..||::::....|||.||:.|:|.:||:|||||:|:.:|.|
Zfish   148 SDVLYTICNNCGPVQRIVIFRK-NGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPT 211

  Fly   597 ALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPP 661
            .|||..|:..:.|:|||:|...:            ||.|.    ..|||              .|
Zfish   212 RLNVFKNDQDTWDYTNPSLGTQD------------MNANP----NKRQR--------------QP 246

  Fly   662 FALGLGTPLTGGYNNALPNLAAFSLANSGALQ---TTAPAMRGYSN------------------- 704
            ..||...|..|||    |.....|....|...   .:||...|.|.
Zfish   247 ALLGDHPPEYGGY----PGYPDESYGYEGRRMGPPMSAPRRGGASQRYSAQYGGPPPPPPGEYGA 307

  Fly   705 -----VLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKL 764
                 |::|..|:...:..|.:|.:|.:||:|:|||.:.:|..:|:::|.:......|:|||:..
Zfish   308 HADSPVIMVYGLDPVKINADRVFNIFCLYGNVERVKFMKSKPGAAMVEMGDCYAVDRAISHLNNN 372

  Fly   765 RLWGKPIRVMASKHQAVQLPKEGQPDAGLT--RDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSN 827
            .|:.:.:.:..||.||:...:..:.|.|..  :||..:..:||..|.......|..||..||..|
Zfish   373 FLFNQKLNLCVSKQQAIMPGQSYELDDGTNSFKDYHGSRNNRFATPEQAAKNRIQHPSNVLHFFN 437

  Fly   828 -IPSS--------CSEDDIKEAFTSNSFEVKAF--KFFPKDRKMA-LLQLLSVEEAVLALIKMHN 880
             :|.:        |.|..:|     |...:|.|  |....||..: ||:..||.:|:.||..:::
Zfish   438 AVPEATPEMFTRLCEEHGVK-----NPSNIKIFVAKGNSPDRSSSGLLEWESVNDAMEALAMINH 497

  Fly   881 HQLSESN-----HLRVSFS 894
            :|:...|     .|::.||
Zfish   498 NQMKNPNGPYPFTLKLCFS 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	149/575 (26%)
hnrnpl2	NP_001410665.1	hnRNP-L_PTB	40..520	CDD:273733	149/575 (26%)