Protein Alignment heph and ptbp2a

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001315358.1
• Gene: ptbp2a / 541437
• ZFINID: ZDB-GENE-050320-141
• Length: 512
• Species: Danio rerio
• Alignment Length: 587
• Identity: 285/587 - (48%)
• Similarity: 378/587 - (64%)
• Gaps: 98/587 - (16%)

  Fly   323 RGSDELLSQAAVMAPA------SDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGE 381
            ||||||||.....:|:      ||..:....:||.::|...    |.|..|:|:|:|.:||:..|
Zfish    13 RGSDELLSGGMYNSPSSGLSSISDTTSNGSDSKKLRVEERV----GDAPPSRVLHIRKLPNDVSE 73

  Fly   382 ADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELK 446
            |::||||:|||:|||:|.||||||||:|::.|.:|.:||:.|:...|.:|...||:|:|||:|||
Zfish    74 AEIIALGLPFGKVTNILTLKGKNQAFLELSTEEAAMTMVNYYSAVTPHVRSVPVYIQYSNHKELK 138

  Fly   447 TDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNA 511
            ||                             |::.:...|:|.|||:.|             :.:
Zfish   139 TD-----------------------------NSSQSGGTSTSGSNSSDG-------------SGS 161

  Fly   512 AGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLL 576
            |..|  |||:|::::.|||:||:|.|||.::|.|:||:||||||.||||:||.|...||.||..|
Zfish   162 ASSP--VLRIIIDNMFYPVTLDVLQQIFSKFGTVMKIITFTKNNQFQALLQYNDPACAQQAKVAL 224

  Fly   577 DGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALP--PGEPGVDIMPTAGGLMNTNDLLL 639
            |||||||.|||||||.|||..||||||||||||:|.|.||  .|:|.:|:
Zfish   225 DGQNIYNACCTLRIDYSKLVNLNVKYNNDKSRDYTRPELPAGDGQPALDV--------------- 274

  Fly   640 IAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSN 704
            .||..:.|.|:.| ..||.|.|.                 :.||.:.|.:|.:     |:.|:|:
Zfish   275 AAALSKDSSSLLG-KIPGALSPL-----------------SAAAAAAAAAGRV-----ALSGHSS 316

  Fly   705 ---VLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRL 766
               ||||||||||||||.:|||||||||||||||||:|||||||||||:..||.||||||:..::
Zfish   317 SGGVLLVSNLNEEMVTPHSLFTLFGVYGDVQRVKILFNKKDSALIQMADMNQAQLAMSHLNGQKM 381

  Fly   767 WGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSS 831
            :.|.|||..||||.||||::|..|.|||:|::.:||||||||||||:|||:||||||||||||..
Zfish   382 FSKIIRVTMSKHQTVQLPRDGLDDQGLTKDFTNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPQD 446

  Fly   832 CSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKS 896
            .:|:|::..|:::...||||||| :|.||||:|:.::|||:..||.:||:.:..::||:||||||
Zfish   447 VTEEDLRVLFSNSGGTVKAFKFF-QDHKMALIQMSTIEEAIQCLIDLHNYNMGNNHHLKVSFSKS 510

  Fly   897 NI 898
            .|
Zfish   511 TI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	268/536 (50%)
ptbp2a	NP_001315358.1	hnRNP-L_PTB	58..512	CDD:273733	268/536 (50%)