Protein Alignment heph and hrpl-1

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001379559.1
• Gene: hrpl-1 / 3565706
• WormBaseID: WBGene00016624
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 131/562 - (23%)
• Similarity: 206/562 - (36%)
• Gaps: 148/562 - (26%)

  Fly   367 SKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMR 431
            |.|:|:||:..:..|||::.....||.|.....:.....|.:|..|                 :.
 Worm    31 SIVVHVRNLHQKVTEADLLEALSNFGPVAYATCIPHSRMALVEFED-----------------IE 78

  Fly   432 GRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGI 496
            |....|.|                                       ||||..|.     ...|.
 Worm    79 GAKACVNF---------------------------------------ATSNQINV-----GGQGA 99

  Fly   497 LQNTS---AVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQ 558
            |.|.|   .:...|..:|.  ||.||.|.|.:..||:..|:::||....||||::....|....|
 Worm   100 LFNYSTSQCIERMGFESAT--PNKVLVVTVLNAQYPIDADVIYQISNAQGKVLRVAVMHKPTVVQ 162

  Fly   559 ALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVD 623
            ||:::.....|:.||..::|.:||:|||||:::.:|...:.|:..:...||||   ||..|
 Worm   163 ALVEFESMEVAKAAKHAMNGADIYSGCCTLKVEFAKPDRVRVQRQDKDQRDFT---LPDNE---- 220

  Fly   624 IMPTAGGLMNTNDLLLIAAR-----QRP--------------SLSVNGLGAPGVLPPFALGLGTP 669
                  ...:|....||.|:     :||              :.|..|..:.|
 Worm   221 ------SFQDTGRKTLIPAKPDDHYRRPYEDDRNHYDRHDYQAPSSYGYSSRG------------ 267

  Fly   670 LTGGYNNAL-----------PNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFT 723
              ||:::..           |:.......:.|..|   ||..|...|:::..|....:..|.||.
 Worm   268 --GGHSDYYGGDRGGPPHPPPSRYRDDYEDRGYAQ---PAGGGPGCVMMIYGLEHGKINCDMLFN 327

  Fly   724 LFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQ------ 782
            :...||:|.|:..:..|.::.:|::..|::....:..|....|:|..:....|..:.|.
 Worm   328 ILCQYGNVLRISFMRTKTETGIIELGTPEERQNVLDFLQGSALFGLTLEFKPSHQECVHHLRDPF 392

  Fly   783 -LPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSF 846
             || :|.|.   .:|||.:...||..|.......|..|:.|||..|.|.:..|..:.:.....:
 Worm   393 LLP-DGSPS---FKDYSSSRNQRFSTPELAAKNRIIFPTNTLHWFNAPGTMDEQALLDLMAEKT- 452

  Fly   847 EVKAFK--FFPKDRK-----MALLQLLSVEEAVLALIKMHNH 881
            |.|..|  .||...:     .|..:.:.:...||||:   ||
 Worm   453 EHKPVKIDIFPSRNERSAAGTAEFETVEIANEVLALV---NH 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	131/562 (23%)
hrpl-1	NP_001379559.1	hnRNP-L_PTB	30..514	CDD:273733	131/562 (23%)