Protein Alignment heph and Hnrnpll

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_233805.5
• Gene: Hnrnpll / 313842
• RGDID: 1305861
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 164/689 - (23%)
• Similarity: 277/689 - (40%)
• Gaps: 189/689 - (27%)

  Fly   297 SPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKA---------- 351
            |.||   ||||:...:|...::....|...|   :..::..|.::.|:..||.:|
  Rat     2 SSTS---SSPKEETYEEDREFESQAKRLKTE---EGEIVYSAEESENRQEATPQAGSDSDSGGGD 60

  Fly   352 ----------------------------------------------KLEPGTVLAGGIAK--ASK 368
                                                          .:.|.|...|...|  .|.
  Rat    61 RGSGGGGGDGEEGDGGEEGDGEEGDEGDGDERGSGGDEGGSGGGPRSMPPSTEGGGSHHKVSVSP 125

  Fly   369 VIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGR 433
            |:|:|.:.....|||::.....||.:..|:::..|.||.:|..:..||...|:.....|..:.|:
  Rat   126 VVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADVPVYIAGQ 190

  Fly   434 MVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQ 498
            ..:..:|..:.
  Rat   191 QAFFNYSTSKR------------------------------------------------------ 201

  Fly   499 NTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQY 563
                :...|||:...|.|.||.:.:::.:||:::|:|:.:....|||.:||.| |.|..||::::
  Rat   202 ----ITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIF-KRNGIQAMVEF 261

  Fly   564 PDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTA 628
            .....||.||:.|:|.:||.|||||:|:.::.|.|||..|::.|.|:|.|.|...:.|
  Rat   262 ESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDRG------- 319

  Fly   629 GGLMNTNDLLLIAARQR--------PSLSVNGLGAPGVLPPFALGLGTPLTGGY---NNALPNLA 682
                        ..|||        .|...:|.|:.|.|        .||...|   :...|.|.
  Rat   320 ------------KGRQRQAILGDHPSSFRHDGYGSHGPL--------LPLPSRYRMGSRDTPELV 364

  Fly   683 AFSL--ANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSAL 745
            |:.|  |:|..:...:|:    .:|::||.|::..:....:|.||.:||::::||.:.....:||
  Rat   365 AYPLPQASSSYMHGGSPS----GSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTAL 425

  Fly   746 IQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPK---EGQPDAGLTRDYSQNPLHRFKK 807
            ::|.:......|::||:.::|:||.:.|..||..:| :|.   |.:......:|::.:..:||..
  Rat   426 VEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSV-VPSQIFELEDGTSSYKDFAMSKNNRFTS 489

  Fly   808 PGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTS--NSFEVKAF-KFFPKDRKMA------LL 863
            .|..:...|.|||..||..|:|...:|    |.||.  |..||..| |:...|.|.:      ||
  Rat   490 AGQASKNIIQPPSCVLHYYNVPLCVTE----ETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLL 550

  Fly   864 QLLSVEEAVLALIKMHNHQLSESN-----HLRVSFSKSN 897
            :.....:||.||..::::|:...|     .|::.||.|:
  Rat   551 EWKCKTDAVEALTALNHYQIRVPNGSNPYTLKLCFSTSS 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	145/562 (26%)
Hnrnpll	XP_233805.5	hnRNP-L_PTB	123..590	CDD:273733	145/562 (26%)