Protein Alignment heph and Ptbp2

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_006233298.1
• Gene: Ptbp2 / 310820
• RGDID: 1359267
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 297/595 - (49%)
• Similarity: 376/595 - (63%)
• Gaps: 90/595 - (15%)

  Fly   323 RGSDELLSQAAVMAPASD--------NNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNES 379
            ||||||||.:.:.:|.|:        |.|.   :||.|.|  ..:.|.   .|:|:|:|.:|.|.
  Rat    14 RGSDELLSGSVLSSPNSNMSGMVVTANGND---SKKFKGE--DKMDGA---PSRVLHIRKLPGEV 70

  Fly   380 GEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRE 444
            .|.:|||||:|||:|||:|:||||||||:|:|.|.:|.:||:.|:...|.:|.:.:|:|:|||:|
  Rat    71 TETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKE 135

  Fly   445 LKTDQGHNN------STAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAV 503
            ||||...|.      ....:..:..:|.||:.:..||...|.|
  Rat   136 LKTDNTLNQRAQVVLQAVTAVQTANTPLSGTTVSESAVTPAQS---------------------- 178

  Fly   504 NAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANS 568
                         .|||:|::::.|||:||:|||||.::|.||||:||||||.||||:||.|..:
  Rat   179 -------------PVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVN 230

  Fly   569 AQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALP--PGEPGVDIMPTAGGL 631
            ||.||..||||||||.|||||||.|||..||||||||||||:|.|.||  .|:|.:|  |.
  Rat   231 AQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALD--PA---- 289

  Fly   632 MNTNDLLLIAARQRPSLSVNGL---GAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQ 693
                    |||......|:.||   ..||.|.|.              |:||.||.:.|.:....
  Rat   290 --------IAAAFAKETSLLGLPVAAVPGALSPL--------------AIPNAAAAAAAAAAGRV 332

  Fly   694 TTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAM 758
            .......|.:.||||||||||||||.:|||||||||||||||||||||||||||||:..|:.|||
  Rat   333 GMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAM 397

  Fly   759 SHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATL 823
            :||:..:::||.|||..||||.||||:||..|.|||:|:..:||||||||||||:|||:||||||
  Rat   398 NHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATL 462

  Fly   824 HLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNH 888
            ||||||.|.:|:|::..|.:....|||||||.:|.||||||:.:||||:.|||.:||:.|.|::|
  Rat   463 HLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQRDHKMALLQMATVEEAIQALIDLHNYNLGENHH 527

  Fly   889 LRVSFSKSNI 898
            ||||||||.|
  Rat   528 LRVSFSKSTI 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	279/542 (51%)
Ptbp2	XP_006233298.1	hnRNP-L_PTB	57..537	CDD:273733	279/542 (51%)