Protein Alignment heph and Rbm20

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_063121392.1
• Gene: Rbm20 / 309544
• RGDID: 1307427
• Length: 1295
• Species: Rattus norvegicus
• Alignment Length: 677
• Identity: 137/677 - (20%)
• Similarity: 217/677 - (32%)
• Gaps: 251/677 - (37%)

  Fly     5 PIPMPMPISSLHKSEFEPVNIGVKQMQLLHAPA---STHPHPHPHQHPQHSAASAAAYQAMQVHQ 66
            |:|.|:|.....:|...         |::...|   ..:|.....|:|  ...|.|:.|..|:..
  Rat    43 PLPPPLPPPPQPQSSLP---------QIIQNAAKLLDKNPFSVSSQNP--LLTSPASVQLAQIQA 96

  Fly    67 Q---QHQQQQQAAVFHHQVAAIAAQQQQQQQQAQVQHQQQMQQQFHYQAQAQAQAQAMLQTYMQL 128
            |   ...:..|.||.::..||...    .|..::|...|.:..|..:        .::|.|
  Rat    97 QLTLHRLKMAQTAVTNNTAAATVL----NQVLSKVAMSQPLFNQLRH--------PSVLGT---- 145

  Fly   129 QVNSAVGVSTAPAT------PTKPVAAQIPGAISGPIAGPVPVSVPTQFFTA----------PST 177
             .:...|||...||      |:..:|...|....||  || .||:|:|...|          |.|
  Rat   146 -THGPTGVSQHAATVPSAHFPSTAIAFSPPSQAGGP--GP-SVSLPSQPPNAMVVHTFSGVVPQT 206

  Fly   178 PLTIIPAAAVASSAMFATAAT--------------------------PTSAATTPTNNVNNTVNL 216
            |..  ||..::......|.||                          |.||:...:..|....:.
  Rat   207 PAQ--PAVILSIGKAGPTPATTGFYDYGKANPGQAYGSETEGQPGFLPASASAAASGGVTYEGHY 269

  Fly   217 SAVSRTTTTTTKK---------------------------------------------------- 229
            |...:....|..|
  Rat   270 SHTGQDGQATFSKDFYGPSAQGSHAAGGFPADQAGSMKGDVGGLLQGTNSQWERPSGFSGQNKAD 334

  Fly   230 -------------QP-------QAVADAVLSAVGGNVGTAVGGGTIS--------SLLGPEPLP- 265
                         ||       :..:|....|.|..:..:..|...|        ::|...||.
  Rat   335 ITAGPGLWAPPASQPYELYDPEEPTSDRAPPAFGSRLNNSKQGFNCSCRRTKEGQAMLSVRPLQG 399

  Fly   266 --------IMPHHLP-LAS---------------VRG-------------------CSSASSGCS 287
                    :.|.||| :.|               |:|                   |::.....|
  Rat   400 HQLNDFRGLAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLLFSESAGLRSICATGEGTLS 464

  Fly   288 SASSDCSMPSPTSLHLSSPKKVRIDEQYIYKL--NYLRGSDELLSQAAVMAPASDNNNQDLATKK 350
            ::::..::.:||.           :|.|...|  :|........:|:..|.| |.::..:.|.:|
  Rat   465 ASANSTAVYNPTG-----------NEDYTSTLGTSYAAIPTRAFAQSNPMFP-SASSGTNFAQRK 517

  Fly   351 AKLEPGTVLAGGIAKASKVIHLRNIPNES-GEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEI 414
            .              |.:|:|:.|:|..| .|.|||.||:|||:|||.:::|..||||:|||...
  Rat   518 G--------------AGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAYTE 568

  Fly   415 SATSMVSCYTVTPPQMRGRMVYVQFS-NHRELKTDQGHNNSTA-----HSD-----------YSV 462
            :|.:||..|...|..:.|..:.::.| .::||:..:...|..|     ||.           |..
  Rat   569 AAQAMVQYYQEKPALINGEKLLIRMSTRYKELQLKKPGKNVAAIIQDIHSQRERCMLREADRYGP 633

  Fly   463 QSPASGSPLPLSAAANATSNNANSSSD 489
            :.|.|.||:..|.:..:.|....|.:|
  Rat   634 ERPRSRSPMSRSLSPRSHSPPGPSRAD 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	48/142 (34%)
Rbm20	XP_063121392.1	None