Protein Alignment heph and Smptb

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_877970.1
• Gene: Smptb / 302879
• RGDID: 727953
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 259/603 - (42%)
• Similarity: 369/603 - (61%)
• Gaps: 62/603 - (10%)

  Fly   337 PASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLK 401
            ||::.|    .:|:.|.:     :.|....|:::|:..:|:...|.:::.|.:|||.|:|:|.|:
  Rat     7 PAAEGN----GSKRFKGD-----SWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLR 62

  Fly   402 GKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPA 466
            .|||||:||:.|.||.:|::.||..||.:||:.|::||:::||||.....:...:.|.......|
  Rat    63 AKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREA 127

  Fly   467 SGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGP-------------NTV 518
            :.|.| ::....|.::...:......|...|....:..||  |.|...|             :.|
  Rat   128 TASSL-VAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAG--TVALAPPASAVDTELVVAWQSPV 189

  Fly   519 LRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYN 583
            ||::||:..|.|:|::|||||.|:|.||||:|.||||.||||:||....||:.||..|||||||:
  Rat   190 LRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYD 254

  Fly   584 GCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSL 648
            .||||||..|.||.|.||||||||||:..|.||..    |..|:...:.|     :.:|...|::
  Rat   255 ACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSD----DSQPSPVQVQN-----MASALPAPAM 310

  Fly   649 SVNGLGAPGVLP-----PFALGLGTP--LTGGYNNALPNLAAFSLANS--------GALQTTAPA 698
            |.....|...||     |.|.||..|  ....:..|:..:|..|.::|        ||.:..|.|
  Rat   311 SSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAA 375

  Fly   699 MRGY-------------SNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAE 750
            :.|.             |.||||:|||:|.|||.:||.|||.||||.|||||:|:|::||:|||:
  Rat   376 VPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMAD 440

  Fly   751 PQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQN 815
            ..||.||:.||:..:|:||.:.::.||||:|:||:||:.|.|||:||:.:||||||||||||:||
  Rat   441 GSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQN 505

  Fly   816 IYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHN 880
            |:||||||||||:||..||:::|..|:||.:.||||:||||:.||||:::.|.|||:.||:.:|.
  Rat   506 IFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHG 570

  Fly   881 HQLSESNHLRVSFSKSNI 898
            |.|.:::|:|||||:..|
  Rat   571 HLLGQNHHMRVSFSRMTI 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	252/572 (44%)
Smptb	NP_877970.1	hnRNP-L_PTB	27..588	CDD:273733	252/572 (44%)