Protein Alignment heph and Ptbp1

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_038934518.1
• Gene: Ptbp1 / 29497
• RGDID: 62047
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 603
• Identity: 325/603 - (53%)
• Similarity: 399/603 - (66%)
• Gaps: 87/603 - (14%)

  Fly   323 RGSDELLSQAAVMAP------ASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGE 381
            ||||||.|......|      ||..|..|  :||.|   |...:.|:  .|:|||:|.:|::..|
  Rat    18 RGSDELFSTCVSNGPFIMSSSASAANGND--SKKFK---GDNRSTGV--PSRVIHVRKLPSDVTE 75

  Fly   382 ADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELK 446
            .:||:||:|||:|||:|:|||||||||||:.|.:|.:||:.||...|.:||:.:|:|||||:|||
  Rat    76 GEVISLGLPFGKVTNLLMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELK 140

  Fly   447 TDQGHNNSTAHSD-YSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTN 510
            ||...|.:.|.:. .:|.|..||:   |:.||:|                     :||:||   .
  Rat   141 TDSSPNQARAQAALQAVNSVQSGN---LALAASA---------------------AAVDAG---M 178

  Fly   511 AAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSL 575
            |..|.:.|||:|||:|.|||:||:|||||.::|.||||:||||||.||||:||.|..||||||..
  Rat   179 AMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLS 243

  Fly   576 LDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLI 640
            ||||||||.|||||||.||||:||||||||||||:|.|.||.|    |..|:.       |..:.
  Rat   244 LDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSG----DSQPSL-------DQTMA 297

  Fly   641 AARQRPSLSVNGLGAPGVL--PPFALGLGTPLTGGYNNALPNLAAFSLAN-SGALQTTA------ 696
            ||          .||||::  .|:| |.|.|.|    .|:|..|..|:.| .|||...|
  Rat   298 AA----------FGAPGIMSASPYA-GAGFPPT----FAIPQAAGLSVPNVHGALAPLAIPSAAA 347

  Fly   697 ----------PAMRGYSN-VLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAE 750
                      |.:.|..| ||||||||.|.|||.:||.||||||||||||||:|||::||:|||:
  Rat   348 AAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMAD 412

  Fly   751 PQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQN 815
            ..||.||||||:..:|.||.:|:..||||:||||:|||.|.|||:||..:||||||||||||:||
  Rat   413 GSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQN 477

  Fly   816 IYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHN 880
            |:||||||||||||.|.||||:|..|:||...||.||||.|||||||:|:.||||||.|||::||
  Rat   478 IFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHN 542

  Fly   881 HQLSESNHLRVSFSKSNI 898
            |.|.|::|||||||||.|
  Rat   543 HDLGENHHLRVSFSKSTI 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	307/552 (56%)
Ptbp1	XP_038934518.1	hnRNP-L_PTB	60..560	CDD:273733	307/552 (56%)