Protein Alignment heph and Ptbp3

DIOPT Version :9

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_006537914.1
• Gene: Ptbp3 / 230257
• MGIID: 1923334
• Length: 556
• Species: Mus musculus
• Alignment Length: 601
• Identity: 308/601 - (51%)
• Similarity: 380/601 - (63%)
• Gaps: 86/601 - (14%)

  Fly   323 RGSDELLSQAAVMAPASDN---------NNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNE 378
            ||||||||...:..|::.|         |..|....|....|        ...|:|:|||.||.:
Mouse    17 RGSDELLSSGVINGPSTMNSSTSAGVYANGNDNKKFKGDRPP--------CSPSRVLHLRKIPCD 73

  Fly   379 SGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHR 443
            ..||:||:||:|||:|||:|:||||:|||:|||.|.:|.:|::.||...|.:|.:.||:|:||||
Mouse    74 VTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHR 138

  Fly   444 ELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAG-- 506
            |||||.                     ||..|.|.|.                ||..|||.:|
Mouse   139 ELKTDN---------------------LPNQARAQAA----------------LQAVSAVQSGNL 166

  Fly   507 ---GNTNAAG----GPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYP 564
               |.|...|    |.:.|||:|:|:|.|||:|::|||||.::|.||||:||||||.||||:||.
Mouse   167 SLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYA 231

  Fly   565 DANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPT-- 627
            |..:||:||..||||||||.|||||||.||||:||||||||||||||...||.|:....:.|.
Mouse   232 DPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMA 296

  Fly   628 ----AGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLAN 688
                |.|:|::           |.....|. ||.:..|.|.||..|...|   ||..|...|.|.
Mouse   297 AAFGAPGIMSS-----------PYAGAAGF-APAIAFPQAAGLSVPAVPG---ALGPLTLTSSAV 346

  Fly   689 SGALQTT-APAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQ 752
            ||.:... |..|.| ::||||:|||.:.:||..||.||||||||.||||::|||::||:|||:..
Mouse   347 SGRMAIPGASGMPG-NSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADAS 410

  Fly   753 QAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIY 817
            ||.|||:||...||:||.:|...|||||||||:|||.|.|||:|:|.:||||||||||||:|||:
Mouse   411 QAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIF 475

  Fly   818 PPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQ 882
            ||||||||||||.|.:.||:|..||.....|||||||.|||||||:||.|||||:.|||::|||.
Mouse   476 PPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHD 540

  Fly   883 LSESNHLRVSFSKSNI 898
            |.|::|||||||||.|
Mouse   541 LGENHHLRVSFSKSTI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	293/547 (54%)
		RRM1_PTBP1_like	368..448	CDD:241132	46/79 (58%)
		RRM2_PTBP1_like	516..611	CDD:241137	68/94 (72%)
		RRM3_PTBP1_like	705..778	CDD:240869	44/72 (61%)
		RRM4_PTBP1_like	822..897	CDD:240871	51/74 (69%)
Ptbp3	XP_006537914.1	hnRNP-L_PTB	61..556	CDD:273733	293/547 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4742
eggNOG	1	0.900	-	-		E1_KOG1190
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	521	1.000	Inparanoid score	I1252
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58575
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	1	1.000	-	-		FOG0001151
OrthoInspector	1	1.000	-	-		otm43656
orthoMCL	1	0.900	-	-		OOG6_101075
Panther	1	1.100	-	-	O	PTHR15592
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4107
SonicParanoid	1	1.000	-	-		X703
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.870